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Common Stock Value 0.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.01
Weighted Average Number Of Diluted Shares Outstanding NA61.1260.5460.14NA59.9159.7759.67NA59.4359.2759.03NA58.8258.5858.37NA51.9851.9351.91NA51.7051.2648.49NA46.7146.54
Weighted Average Number Of Shares Outstanding Basic NA61.1260.5460.14NA59.9159.7759.67NA59.4359.2759.03NA58.8258.5858.37NA51.9851.9351.91NA51.7051.2648.49NA46.7146.54
Earnings Per Share Basic -1.56-1.53-1.70-1.80-0.54-3.37-2.68-2.46-2.47-2.31-2.13-2.07-2.11-2.21-1.83NA18.71-2.03-2.63-2.44NANANANANANANA
Earnings Per Share Diluted -1.56-1.53-1.70-1.80-0.54-3.37-2.68-2.46-2.47-2.31-2.13-2.07-2.11-2.21-1.83NA18.19-2.03-2.63-2.44NANANANANANANA

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Revenues 12.8211.878.657.9077.972.722.473.292.871.741.501.581.641.441.641.581109.191.641.092.291.963.570.870.470.270.0090.00
Operating Expenses 115.01113.07119.95125.58120.05214.56172.93158.76156.77143.22129.91124.78127.13132.33109.6698.09135.21108.80140.06133.91176.60190.75177.33170.32164.50128.75112.15
Research And Development Expense 37.0254.5862.5671.7364.33101.9297.1692.8389.3081.5577.3078.0275.4483.5066.1758.0681.7174.0873.3263.6191.25102.1189.0686.4088.8175.0568.98
Selling General And Administrative Expense 54.6553.2255.9852.5755.1178.1475.5665.7167.3361.4852.4146.4851.6048.7143.3539.8553.5035.1038.2270.1385.1388.5088.2383.9275.6953.6943.17
Operating Income Loss -102.19-101.20-111.30-117.67-42.07-211.85-170.46-155.47-153.90-141.48-128.41-123.20-125.49-130.89-108.02-96.51973.98-107.16-138.97-131.62-174.64-187.18-176.46-169.85-164.23-128.75-22.15
Interest Income Expense Nonoperating Net 6.407.648.439.209.4710.2710.178.836.794.132.101.170.750.690.730.710.831.352.694.735.927.238.226.445.855.825.14
Allocated Share Based Compensation Expense 9.4314.2117.1713.7012.9528.6911.6920.0415.2413.1714.6418.5520.6534.3427.6621.9820.7420.1124.0331.1130.6843.6734.7744.1231.6425.4829.03
Profit Loss -95.78-93.55-102.85-108.48-32.71-201.63-160.32-146.83-147.15-137.32-126.26-122.06-124.71-130.17-107.25-95.76974.89-105.73-136.35-126.74-168.65-179.96-168.22-163.41-158.39-122.92-16.98
Net Income Loss -95.78-93.55-102.85-108.48-32.71-201.63-160.32-146.83-147.15-137.32-126.26-122.06-124.71-130.17-107.25-95.76974.89-105.73-136.35-126.74-168.65-179.96-168.22-163.41-158.39-122.92-16.98
Comprehensive Income Net Of Tax -96.44-91.96-102.76-108.46-29.79-199.72-160.88-141.71-142.47-138.33-128.93-130.60-127.07-130.19-107.29-96.42974.36-106.50-133.85-128.83-169.13-179.76-166.54-163.00-158.65-123.03-16.94

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Assets 547.22622.43697.11767.60882.28949.661082.291220.691356.451486.071601.381705.701825.291927.182015.472080.702159.25738.63827.24944.971084.151203.731315.551422.91952.711047.001129.48
Liabilities 82.1370.6069.0461.8082.75133.0097.9187.56103.85105.9597.1487.2096.2691.5385.9677.4286.9181.0587.3395.77139.50122.66112.67103.3889.7358.4951.72
Liabilities And Stockholders Equity 547.22622.43697.11767.60882.28949.661082.291220.691356.451486.071601.381705.701825.291927.182015.472080.702159.25738.63827.24944.971084.151203.731315.551422.91952.711047.001129.48
Stockholders Equity 465.09551.84628.06705.80799.53816.66984.381133.131252.601380.121504.241618.501729.031835.651929.512003.282072.33657.58739.91849.21944.651081.071202.881319.53862.97988.501077.76

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Assets Current 531.30604.99686.81755.44869.35933.271064.031203.441336.981465.101578.881682.241800.641901.701988.602051.872122.37698.88785.38898.241035.091152.661263.571371.53944.701039.911123.77
Cash And Cash Equivalents At Carrying Value 81.0299.6399.90172.6570.99148.71121.42206.56162.70199.83206.51178.67294.23422.17514.16899.251661.08184.27258.23199.44126.70259.18166.19342.30190.94253.12325.83
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents 82.47NANANA72.32NANANA163.97NANANANANANANANANANANANANANANA193.31255.04327.10
Marketable Securities Current 423.40469.53546.89544.36682.19727.34881.20923.031109.791193.811307.201446.571448.061421.001397.161104.77438.47484.27498.29673.31881.69863.071070.361008.96731.83768.28766.60
Accounts Receivable Net Current 9.1314.879.9410.5183.0122.51NANA13.66NANANANANANANANANANANANANANANANANA18.38
Prepaid Expense And Other Assets Current 17.7519.6328.7426.5931.8234.7046.3258.8550.8353.0241.4537.2139.8434.3428.8523.0822.8230.3528.8625.4826.7030.4127.0220.2821.9218.5112.96

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Property Plant And Equipment Gross 1.67NANANA9.41NANANA8.99NANA8.097.997.967.968.8213.8413.8413.9113.8513.6213.2011.509.147.867.026.01
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment 0.78NANANA7.49NANANA6.09NANA5.254.975.054.674.657.096.445.835.174.503.833.142.632.221.851.57
Property Plant And Equipment Net 0.891.021.271.581.922.442.482.662.902.822.942.843.022.913.284.176.757.408.088.689.139.378.366.515.645.174.45
Other Assets Noncurrent 2.835.177.806.226.556.596.894.254.774.914.914.594.253.883.603.393.343.433.423.693.79NANANANANANA
Available For Sale Debt Securities Amortized Cost Basis 423.15468.63547.58545.15683.01731.08886.84928.111120.001208.701321.071457.771450.721421.311397.441105.00438.05483.32496.58674.11880.39861.291068.791009.06732.35768.53766.75

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Liabilities Current 71.6160.4169.0461.8082.75133.0096.8184.6999.2699.6989.2477.7085.1978.9471.9062.0167.2059.6664.2970.36112.1390.9678.9568.3886.0354.5347.92
Accounts Payable Current 12.707.138.656.4810.3211.149.2812.2618.957.085.417.1310.454.732.923.293.694.292.397.9115.275.0412.4313.5634.045.888.34
Other Accrued Liabilities Current 0.580.370.440.550.710.660.870.810.560.520.510.520.620.660.730.690.500.971.061.150.950.890.533.300.240.170.46
Accrued Liabilities Current 57.6053.2058.9852.0167.26114.9079.8064.7572.6785.0176.2763.0567.2866.8061.6251.4254.8546.7653.3352.1886.6278.1358.9147.6551.9948.6539.58

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Operating Lease Liability Noncurrent 10.5210.19NANANANA1.002.764.496.167.809.4010.9612.4813.9615.4119.4421.0722.6624.9526.8531.3633.31NANANANA

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Stockholders Equity 465.09551.84628.06705.80799.53816.66984.381133.131252.601380.121504.241618.501729.031835.651929.512003.282072.33657.58739.91849.21944.651081.071202.881319.53862.97988.501077.76
Common Stock Value 0.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.010.01
Additional Paid In Capital Common Stock 3435.563425.883410.143385.123370.403357.743325.743313.613291.373276.423262.203247.543227.473207.033170.693137.163109.812669.422645.262620.702587.322554.602496.652446.771827.021793.911760.14
Retained Earnings Accumulated Deficit -2970.32-2874.55-2781.00-2678.14-2569.66-2536.95-2335.32-2175.00-2028.17-1881.02-1743.70-1617.44-1495.39-1370.67-1240.50-1133.26-1037.49-2012.39-1906.65-1770.31-1643.57-1474.91-1294.96-1126.73-963.33-804.94-682.02
Accumulated Other Comprehensive Income Loss Net Of Tax 0.240.90-0.69-0.79-0.81-3.73-5.64-5.09-10.21-14.88-13.87-11.20-2.66-0.31-0.28-0.240.410.951.71-0.791.291.781.57-0.11-0.52-0.26-0.14
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value NA13.9516.9513.17NA28.3511.2819.57NA12.7214.6518.27NA34.0827.4621.73NA19.8624.1730.22NA43.0534.2843.62NA25.1828.78

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Net Cash Provided By Used In Operating Activities -66.56-82.36-80.44-37.83-119.52-135.87-131.52-153.68-126.93-118.86-106.44-107.80-97.50-68.83-102.77-109.091010.97-91.02-118.98-136.69-116.73-128.70-133.34-149.93-101.78-80.19-0.14
Net Cash Provided By Used In Investing Activities 46.5781.05-0.39139.4442.06160.3945.59194.8789.78110.95134.26-9.56-30.26-24.98-288.39-658.8245.5213.51177.38206.27-17.92207.78-58.11-274.9138.420.05-238.13
Net Cash Provided By Used In Financing Activities -0.001.048.071.56-0.262.770.852.670.031.230.011.80-0.171.826.075.62419.673.540.393.162.1713.9215.34576.201.638.086.54

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Net Cash Provided By Used In Operating Activities -66.56-82.36-80.44-37.83-119.52-135.87-131.52-153.68-126.93-118.86-106.44-107.80-97.50-68.83-102.77-109.091010.97-91.02-118.98-136.69-116.73-128.70-133.34-149.93-101.78-80.19-0.14
Net Income Loss -95.78-93.55-102.85-108.48-32.71-201.63-160.32-146.83-147.15-137.32-126.26-122.06-124.71-130.17-107.25-95.76974.89-105.73-136.35-126.74-168.65-179.96-168.22-163.41-158.39-122.92-16.98
Profit Loss -95.78-93.55-102.85-108.48-32.71-201.63-160.32-146.83-147.15-137.32-126.26-122.06-124.71-130.17-107.25-95.76974.89-105.73-136.35-126.74-168.65-179.96-168.22-163.41-158.39-122.92-16.98
Increase Decrease In Accounts Payable 5.57-1.522.17-3.84-0.821.89-3.02-6.5511.791.87-1.97-3.255.651.82-0.37-0.41-0.601.90-5.51-7.3110.17-7.15-1.30-20.5127.91-2.47-0.03
Share Based Compensation 9.4314.2117.1713.7012.9528.6911.6920.0415.2413.1714.6418.5520.6534.3427.6621.9820.7420.1124.0331.1130.6843.6734.7744.1231.6425.4829.03

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Net Cash Provided By Used In Investing Activities 46.5781.05-0.39139.4442.06160.3945.59194.8789.78110.95134.26-9.56-30.26-24.98-288.39-658.8245.5213.51177.38206.27-17.92207.78-58.11-274.9138.420.05-238.13

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Net Cash Provided By Used In Financing Activities -0.001.048.071.56-0.262.770.852.670.031.230.011.80-0.171.826.075.62419.673.540.393.162.1713.9215.34576.201.638.086.54

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Revenues 12.8211.878.657.9077.972.722.473.292.871.741.501.581.641.441.641.581109.191.641.092.291.963.570.870.470.270.0090.00
Collaboration Revenue Related Party 11.4311.037.426.21NANANANANANANANANANANANANANANANANANANANANANANA
Other Collaboration Revenue 0.950.000.63NA0.160.000.01NANANANANANANANANANANANANANANANANANANANA
Product 0.440.840.601.691.992.722.463.292.871.741.501.58NANANA1.581.691.641.092.291.961.480.52NANANANA
Collaboration Revenue, Shionogi Collaboration Agreement 0.000.000.60NA-13.8013.990.01NANANANANANANANANANANANANANANANANANANANA
Collaboration Revenue Related Party, Biogen Collaboration Agreement 11.4311.037.426.21NANANANANANANANANANANANANANANANANANANANANANANA

Plots across concepts


IncomeStatement
Operating Income Loss
Balance Sheet
Operating Lease Right Of Use Asset
Assets
Property Plant And Equipment Net
Current Assets
Accounts Receivable Net Current
NonCurrent Assets
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
Liabilities
Operating Lease Liability
Current Liabilities
Other Accrued Liabilities Current
Stockholders Equity
Retained Earnings Accumulated Deficit
CashFlow
Net Income Loss
NetCashProvidedByUsedInOperatingActivities
Net Income Loss
Shares
Weighted Average Number Of Diluted Shares Outstanding
OperatingLeaseLiability
Operating Lease Liability Current
LesseeOperatingLeaseLiabilityPaymentsDue
Lessee Operating Lease Liability Payments Remainder Of Fiscal Year

Line plots across dimensions of each concept