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		2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2016-12-31	2016-09-30	2016-06-30
Common Stock Value		0.07	0.07	0.07	0.07	0.07	0.07	0.07	0.07	0.07	0.07	0.07	0.07	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.05	0.05	0.05	0.05	0.04	0.04	0.04	0.04	0.04
dei: Entity Common Stock Shares Outstanding		NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Weighted Average Number Of Diluted Shares Outstanding		NA	NA	NA	NA	70.05	NA	NA	NA	67.88	67.61	NA	NA	NA	61.15	NA	NA	NA	57.52	53.21	NA	NA	NA	49.08	NA	NA	NA	NA	NA
Weighted Average Number Of Share Outstanding Basic And Diluted		NA	NA	NA	NA	NA	69.93	69.52	NA	67.88	67.61	67.10	NA	60.69	NA	58.00	NA	57.71	57.52	53.21	NA	50.32	49.82	NA	NA	42.47	NA	39.55	39.03
Earnings Per Share Basic		-2.23	-2.25	-2.33	-2.16	-3.50	-2.26	-2.19	-1.79	-1.08	-1.81	NA	-0.37	-1.13	0.42	-2.05	NA	NA	-1.72	-1.82	-1.73	-1.74	-1.06	0.63	NA	NA	NA	NA	NA
Earnings Per Share Diluted		-2.23	-2.25	-2.33	-2.16	-3.50	-2.26	-2.19	-1.79	-1.08	-1.81	NA	-0.37	-1.13	0.41	-2.05	NA	NA	-1.72	-1.82	-1.73	-1.74	-1.06	0.62	NA	NA	NA	NA	NA
Earnings Per Share Basic And Diluted		NA	NA	NA	NA	NA	-2.26	-2.19	-1.79	-1.08	-1.81	-2.03	-0.34	-1.13	NA	-2.05	-1.62	-1.96	-1.72	-1.82	-1.75	-1.74	-1.06	NA	-1.89	-1.87	-1.75	-1.64	-1.46

		2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2016-12-31	2016-09-30	2016-06-30
Revenue From Contract With Customer Excluding Assessed Tax		98.05	108.31	100.50	103.35	90.70	89.34	79.94	83.39	81.65	86.97	99.39	91.54	81.47	61.71	36.31	35.59	25.80	24.15	18.17	16.26	11.76	12.79	10.68	2.41	0.20	0.01	0.11	0.02
Revenues		98.05	108.31	100.50	103.35	90.70	89.34	79.94	83.39	81.65	86.97	99.39	91.54	81.47	61.71	36.31	35.59	25.80	24.15	18.17	16.26	11.76	12.79	10.68	2.41	0.20	0.01	0.11	0.02
Research And Development Expense		157.25	164.95	165.70	170.81	237.30	154.53	143.16	123.01	113.42	113.20	147.52	131.10	87.31	80.71	112.96	83.06	100.14	96.05	78.11	71.62	70.04	76.83	75.50	61.53	60.41	50.75	48.71	43.33
Selling General And Administrative Expense		74.92	81.40	76.65	72.85	69.84	68.14	67.31	59.43	53.88	53.41	53.26	51.04	42.12	42.25	47.52	41.88	41.01	39.81	38.83	34.48	31.09	30.72	31.43	37.72	23.50	NA	NA	NA
Operating Income Loss		-145.10	-147.96	-154.10	-145.63	-225.07	-141.59	-136.63	-102.56	-89.83	-82.78	-106.57	-96.08	-50.31	-63.05	-120.67	-94.45	-118.03	-112.47	-99.21	-90.34	-89.65	-94.90	-96.49	-96.83	-83.71	-70.55	-65.78	-58.05
Allocated Share Based Compensation Expense		34.88	34.65	31.94	29.36	35.76	35.87	29.39	26.55	26.99	27.14	24.30	22.81	20.34	22.41	20.17	19.66	19.91	22.21	20.22	21.08	20.67	19.56	18.80	19.54	17.18	13.54	13.69	10.86
Income Tax Expense Benefit		0.65	0.73	0.49	-1.45	6.29	0.30	0.56	0.02	0.18	0.46	0.38	0.07	0.31	0.41	0.41	2.56	0.29	0.21	0.22	0.13	0.25	0.10	0.04	-16.22	0.00	NA	NA	NA
Other Comprehensive Income Loss Net Of Tax		0.85	0.87	2.61	3.65	-1.31	-2.36	-5.15	-1.46	-0.18	0.18	-0.63	-0.32	-0.27	2.83	-1.40	-0.08	-0.33	0.40	0.48	-0.22	0.24	0.29	4.73	1.72	-3.18	0.89	-0.24	0.16
Net Income Loss		-159.65	-159.83	-163.97	-151.83	-245.11	-158.16	-152.32	-122.46	-73.00	-122.43	-136.14	-24.01	-68.84	25.32	-119.03	-93.81	-112.99	-99.17	-96.76	-87.83	-87.31	-52.73	30.25	-81.73	-79.23	-71.29	-64.91	-56.92
Comprehensive Income Net Of Tax		-158.79	-158.96	-161.37	-148.18	-246.41	-160.52	-157.47	-123.92	-73.18	-122.25	-136.77	-24.34	-69.12	28.14	-120.42	-93.88	-113.32	-98.77	-96.27	-88.05	-87.07	-52.44	34.99	-80.01	-82.41	-70.39	-65.15	-56.76

		2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2016-12-31	2016-09-30	2016-06-30
Assets		1238.14	1311.31	1383.40	1545.44	1618.47	1320.63	1384.03	1522.40	1484.80	1512.44	1597.76	1759.56	1268.38	1314.04	1233.14	1135.50	879.94	958.93	1007.76	719.56	765.14	806.02	817.35	490.75	435.05	540.63	515.17	481.95
Liabilities		1206.43	1182.28	1162.92	1192.95	1149.64	642.55	587.61	599.84	551.13	540.27	543.18	605.18	602.19	618.45	623.99	481.73	152.68	139.14	121.03	110.65	102.55	102.05	93.69	107.30	69.49	66.65	59.28	38.06
Liabilities And Stockholders Equity		1238.14	1311.31	1383.40	1545.44	1618.47	1320.63	1384.03	1522.40	1484.80	1512.44	1597.76	1759.56	1268.38	1314.04	1233.14	1135.50	879.94	958.93	1007.76	719.56	765.14	806.02	817.35	490.75	435.05	540.63	515.17	481.95
Stockholders Equity		31.71	129.03	220.48	352.49	468.83	678.07	796.42	922.56	933.67	972.17	1054.58	1154.38	666.19	695.59	609.15	653.76	727.26	819.79	886.73	608.91	662.60	703.97	723.66	383.45	365.56	473.97	455.89	443.89

		2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2016-12-31	2016-09-30	2016-06-30
Assets Current		599.19	702.14	766.34	883.90	1012.67	678.54	707.52	856.60	846.88	949.49	1070.94	1295.30	872.00	906.04	894.32	851.02	613.49	699.43	786.89	522.37	567.48	604.74	581.58	269.58	390.90	401.69	416.79	411.08
Cash And Cash Equivalents At Carrying Value		72.58	102.06	85.77	132.94	391.65	159.87	153.99	307.58	197.54	290.88	383.79	713.53	197.49	335.64	298.19	433.58	122.58	131.34	269.71	113.43	82.96	110.85	226.73	100.49	60.41	161.12	142.28	55.07
Accounts Receivable Net Current		79.26	70.52	42.99	40.45	31.16	37.21	28.37	28.43	25.38	24.72	25.03	23.09	27.76	14.89	29.33	32.84	23.12	20.90	15.63	12.74	9.15	17.43	3.67	5.17	NA	NA	NA	NA
Inventory Net		31.80	28.26	26.62	26.77	21.85	21.08	17.81	16.23	15.19	15.08	12.46	13.05	14.46	11.06	11.38	11.55	14.14	13.63	10.95	7.07	5.56	3.34	2.07	0.76	NA	NA	NA	NA
Inventory Finished Goods		12.63	9.72	11.53	9.28	6.07	4.89	5.82	5.73	5.64	5.63	5.68	5.86	4.25	3.38	3.14	3.35	3.38	2.57	2.19	1.68	0.96	0.46	0.26	0.02	NA	NA	NA	NA
Prepaid Expense And Other Assets Current		46.03	51.38	67.38	68.93	70.98	77.46	63.02	71.75	69.19	63.93	68.03	57.63	64.26	58.20	64.79	51.40	49.17	46.61	44.99	42.86	49.67	36.84	33.95	28.70	19.38	20.14	18.94	17.80
Available For Sale Securities Debt Securities		495.81	593.41	689.99	876.63	975.07	677.48	791.58	968.31	NA	NA	NA	1172.91	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA

		2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2016-12-31	2016-09-30	2016-06-30
Property Plant And Equipment Gross		NA	NA	NA	323.11	NA	NA	NA	191.28	NA	NA	NA	110.91	NA	NA	NA	70.34	NA	NA	NA	38.25	NA	NA	NA	32.83	NA	23.22	NA	NA
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment		NA	NA	NA	63.38	NA	NA	NA	50.04	NA	NA	NA	37.39	NA	NA	NA	25.99	NA	NA	NA	18.21	NA	NA	NA	10.99	NA	6.16	NA	NA
Property Plant And Equipment Net		296.81	288.99	277.87	259.73	234.61	207.38	177.07	141.25	119.07	104.57	87.57	73.52	48.77	48.34	47.60	44.35	31.88	25.32	21.70	20.05	19.83	20.86	20.83	21.84	16.03	17.05	18.23	17.05
Intangible Assets Net Excluding Goodwill		157.30	158.24	159.17	160.10	158.40	159.20	159.99	130.79	130.87	130.95	131.03	131.11	131.19	131.28	129.00	129.00	129.02	129.07	129.09	129.22	130.23	132.78	137.12	141.54	NA	NA	NA	NA
Finite Lived Intangible Assets Net		NA	NA	NA	31.11	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Other Assets Noncurrent		27.90	26.49	22.26	16.85	18.29	21.14	21.22	20.56	16.42	12.67	8.93	8.81	5.09	2.63	4.86	3.47	3.11	3.18	2.66	3.51	3.20	3.24	1.57	1.31	1.34	1.84	1.87	1.45
Available For Sale Debt Securities Amortized Cost Basis		497.40	596.10	693.25	882.36	983.96	685.49	797.95	969.59	NA	NA	NA	1172.65	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA

		2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2016-12-31	2016-09-30	2016-06-30
Liabilities Current		253.98	244.38	218.18	261.21	227.36	220.64	167.23	181.37	135.93	127.07	127.04	189.61	201.19	219.73	196.86	103.30	90.31	75.01	66.88	74.72	66.68	66.05	57.58	71.01	64.26	60.26	50.43	31.98
Accounts Payable Current		33.36	42.12	58.98	43.27	23.53	34.21	23.68	17.14	15.57	21.79	15.74	12.92	10.85	9.01	14.40	12.87	13.46	8.74	12.66	12.28	8.20	10.31	7.57	8.89	9.29	5.36	6.62	6.95
Other Accrued Liabilities Current		50.80	51.86	45.88	52.18	59.93	54.70	44.63	42.08	32.24	26.96	25.39	24.44	16.16	14.33	13.65	18.98	16.90	11.33	9.56	9.10	8.45	8.25	7.38	8.09	6.65	5.08	4.03	4.61
Accrued Liabilities Current		178.62	167.66	144.40	204.68	189.05	170.35	126.36	145.56	109.66	91.06	82.70	108.49	79.65	71.89	67.72	83.19	69.56	59.26	48.96	62.45	58.48	55.73	49.29	61.43	54.28	54.55	43.49	24.71
Contract With Customer Liability Current		NA	NA	NA	NA	NA	4.44	5.87	9.08	NA	3.91	25.09	66.57	102.90	134.90	NA	NA	0.02	0.06	NA	NA	NA	1.24	NA	5.99	NA	NA	NA	NA

		2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2016-12-31	2016-09-30	2016-06-30
Deferred Income Tax Liabilities Net		31.67	31.67	31.67	31.67	33.31	33.31	33.31	33.31	33.31	33.31	33.31	33.31	33.31	33.31	NA	33.31	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Other Liabilities Noncurrent		10.23	10.39	9.26	4.82	4.05	3.77	3.39	1.00	0.47	NA	NA	7.35	NA	NA	NA	NA	NA	NA	NA	4.76	4.70	4.84	4.94	5.12	5.23	6.39	8.85	6.07
Operating Lease Liability Noncurrent		NA	NA	NA	19.81	NA	NA	NA	30.49	NA	NA	NA	38.55	36.67	36.31	34.96	29.76	31.21	32.97	22.98	NA	NA	NA	NA	NA	NA	NA	NA	NA

		2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2016-12-31	2016-09-30	2016-06-30
Stockholders Equity		31.71	129.03	220.48	352.49	468.83	678.07	796.42	922.56	933.67	972.17	1054.58	1154.38	666.19	695.59	609.15	653.76	727.26	819.79	886.73	608.91	662.60	703.97	723.66	383.45	365.56	473.97	455.89	443.89
Common Stock Value		0.07	0.07	0.07	0.07	0.07	0.07	0.07	0.07	0.07	0.07	0.07	0.07	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.05	0.05	0.05	0.05	0.04	0.04	0.04	0.04	0.04
Additional Paid In Capital		3298.36	3236.88	3169.37	3140.02	3108.17	3071.00	3028.83	2997.50	2884.70	2850.02	2810.18	2773.20	2260.68	2220.96	2162.67	2086.86	2066.48	2045.68	2013.86	1639.77	1605.41	1559.72	1526.97	1221.76	1123.86	1003.56	915.08	837.94
Retained Earnings Accumulated Deficit		-3264.47	-3104.82	-2944.99	-2781.02	-2629.19	-2384.08	-2225.92	-2073.60	-1951.14	-1878.14	-1755.72	-1619.58	-1595.57	-1526.72	-1552.04	-1433.01	-1339.20	-1226.21	-1127.04	-1030.28	-942.46	-855.15	-802.42	-832.67	-750.94	-530.53	-459.25	-394.34
Accumulated Other Comprehensive Income Loss Net Of Tax		-2.24	-3.10	-3.97	-6.57	-10.22	-8.91	-6.55	-1.40	0.05	0.23	0.06	0.69	1.01	1.28	-1.54	-0.15	-0.07	0.26	-0.15	-0.63	-0.41	-0.65	-0.95	-5.68	-7.40	0.91	0.01	0.25
Treasury Stock Value		0.38	0.38	0.36	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value		36.24	34.43	30.10	29.85	36.10	36.19	29.58	26.94	27.00	27.10	24.22	22.72	20.53	22.43	20.16	19.17	19.89	22.49	20.48	22.14	20.67	19.56	18.80	NA	NA	NA	NA	NA

		2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2016-12-31	2016-09-30	2016-06-30
Net Cash Provided By Used In Operating Activities		-117.87	-116.16	-156.87	-90.34	-95.34	-77.26	-117.52	-54.34	-59.65	-65.36	-159.35	-62.45	-61.97	87.35	-95.15	-72.04	-88.51	-89.06	-95.78	-55.85	-69.16	-76.08	-89.48	-81.82	-61.99	NA	NA	NA
Net Cash Provided By Used In Investing Activities		64.30	99.42	111.30	-171.60	-161.86	79.17	-37.36	69.06	-40.76	-41.25	-182.42	97.90	-95.76	-86.14	-95.12	67.27	79.31	-58.43	-101.19	73.56	16.20	-52.07	-71.03	57.39	29.79	NA	NA	NA
Net Cash Provided By Used In Financing Activities		25.23	33.02	-0.72	1.88	491.88	5.84	1.61	85.72	7.55	12.63	12.65	489.71	19.14	35.81	55.62	315.44	0.90	9.34	353.62	12.24	25.02	13.17	286.42	64.44	1.33	NA	NA	NA

		2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2016-12-31	2016-09-30	2016-06-30
Net Cash Provided By Used In Operating Activities		-117.87	-116.16	-156.87	-90.34	-95.34	-77.26	-117.52	-54.34	-59.65	-65.36	-159.35	-62.45	-61.97	87.35	-95.15	-72.04	-88.51	-89.06	-95.78	-55.85	-69.16	-76.08	-89.48	-81.82	-61.99	NA	NA	NA
Net Income Loss		-159.65	-159.83	-163.97	-151.83	-245.11	-158.16	-152.32	-122.46	-73.00	-122.43	-136.14	-24.01	-68.84	25.32	-119.03	-93.81	-112.99	-99.17	-96.76	-87.83	-87.31	-52.73	30.25	-81.73	-79.23	-71.29	-64.91	-56.92
Depreciation Depletion And Amortization		7.19	5.36	5.24	4.96	4.69	4.48	4.09	3.53	3.22	3.12	3.37	3.13	3.09	3.18	2.85	2.17	2.15	2.11	2.12	2.94	4.36	6.08	6.16	2.51	1.09	1.16	1.03	0.69
Increase Decrease In Accounts Receivable		6.20	15.08	2.51	9.10	-5.93	8.94	-0.03	3.07	0.69	-0.32	1.99	-4.71	12.83	-14.46	-3.50	9.70	2.24	5.26	2.90	3.60	-8.27	13.75	-1.50	NA	NA	NA	NA	NA
Increase Decrease In Inventories		3.47	1.66	-0.15	4.21	0.79	3.23	1.48	0.99	-0.05	2.65	-0.47	-1.29	3.16	-0.37	-0.15	-2.15	0.56	2.39	3.65	0.48	2.21	1.27	1.31	NA	NA	NA	NA	NA

		2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2016-12-31	2016-09-30	2016-06-30
Net Cash Provided By Used In Investing Activities		64.30	99.42	111.30	-171.60	-161.86	79.17	-37.36	69.06	-40.76	-41.25	-182.42	97.90	-95.76	-86.14	-95.12	67.27	79.31	-58.43	-101.19	73.56	16.20	-52.07	-71.03	57.39	29.79	NA	NA	NA
Payments To Acquire Property Plant And Equipment		3.69	13.94	25.03	26.97	26.05	30.92	32.18	16.05	20.56	20.07	16.41	21.95	3.78	4.08	14.10	11.50	5.03	5.24	3.06	1.19	1.03	1.38	0.47	0.90	1.03	0.67	3.00	5.04

		2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2016-12-31	2016-09-30	2016-06-30
Net Cash Provided By Used In Financing Activities		25.23	33.02	-0.72	1.88	491.88	5.84	1.61	85.72	7.55	12.63	12.65	489.71	19.14	35.81	55.62	315.44	0.90	9.34	353.62	12.24	25.02	13.17	286.42	64.44	1.33	NA	NA	NA

		2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2016-12-31	2016-09-30	2016-06-30
Revenues		98.05	108.31	100.50	103.35	90.70	89.34	79.94	83.39	81.65	86.97	99.39	91.54	81.47	61.71	36.31	35.59	25.80	24.15	18.17	16.26	11.76	12.79	10.68	2.41	0.20	0.01	0.11	0.02
Daiichi Sankyo Co Ltd, Collaboration And License		0.00	0.00	1.48	1.48	1.48	1.48	3.25	8.23	12.06	21.96	42.75	37.50	32.87	18.86	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Collaboration And License		0.00	19.80	51.38	68.38	52.83	53.09	48.41	58.44	55.05	63.94	79.01	75.02	66.92	50.16	27.21	28.42	21.59	19.25	14.24	12.80	9.02	10.52	9.36	NA	NA	NA	NA	NA
Product		42.35	42.18	44.23	28.91	32.50	30.83	26.68	20.21	21.95	18.35	16.51	12.96	11.21	8.07	6.48	7.17	4.21	4.90	3.93	3.46	2.75	2.27	1.31	0.28	0.20	NA	NA	NA
Royalty		55.70	46.33	4.88	6.06	5.37	5.42	4.84	4.74	4.65	4.69	3.87	3.57	3.33	3.48	2.62	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Product, License Agreement Terms, Kyowa Kirin Collaboration		NA	NA	NA	7.70	13.20	12.40	9.40	5.20	7.40	2.90	5.90	3.00	3.30	2.50	1.60	1.60	1.10	1.00	0.60	0.30	0.30	NA	NA	NA	NA	NA	NA	NA
Collaboration, United States And Canada, Kyowa Kirin Collaboration		0.00	19.80	NA	NA	51.35	51.61	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Collaboration And Royalty, European Union And Switzerland And Turkey, Kyowa Kirin Collaboration		NA	NA	NA	NA	NA	NA	4.84	0.00	0.02	0.23	3.87	-0.00	0.00	1.50	NA	2.22	1.95	1.93	2.02	NA	NA	NA	NA	NA	NA	NA	NA	NA
Collaboration And Royalty, United States And Canada, Kyowa Kirin Collaboration		50.23	61.31	49.91	66.90	51.35	51.61	45.16	50.21	42.97	41.76	36.26	37.52	34.06	29.81	27.21	26.15	19.53	17.25	11.94	NA	NA	NA	NA	NA	NA	NA	NA	NA
Non Cash Royalty, European Union And Switzerland And Turkey, Kyowa Kirin Collaboration		5.47	4.82	NA	NA	5.37	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Non Cash Royalty, United States And Canada, Kyowa Kirin Collaboration		15.07	12.45	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Royalty, European Union And Switzerland And Turkey, Kyowa Kirin Collaboration		NA	4.82	4.88	6.06	5.37	5.42	50.00	4.74	4.65	4.69	3.87	3.57	3.33	3.48	2.62	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Royalty, United States And Canada, Kyowa Kirin Collaboration		35.16	29.06	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Collaboration And License, Crysvita		0.00	19.80	49.91	66.90	51.35	51.61	45.16	50.21	42.97	41.76	36.26	37.52	34.06	29.81	27.21	26.15	19.53	17.25	11.94	NA	NA	NA	NA	NA	NA	NA	NA	NA
Collaboration And Royalty, Kyowa Kirin Collaboration		74.90	83.01	76.02	72.96	56.72	57.03	59.40	54.95	47.64	46.67	40.13	41.09	37.39	34.79	29.83	28.37	21.48	19.18	13.95	NA	NA	NA	NA	NA	NA	NA	NA	NA
Product, Crysvita		19.20	16.88	21.23	7.70	13.18	12.40	9.39	5.27	7.38	2.90	5.87	2.91	3.28	2.55	1.61	1.55	1.14	1.01	0.59	0.35	0.27	0.03	NA	NA	NA	NA	NA	NA
Product, Dojolvi		16.55	16.49	14.30	16.41	13.27	13.50	12.43	11.82	10.65	10.05	7.03	6.39	3.86	1.33	1.44	1.26	0.71	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Product, Evkeeza		0.96	0.36	0.21	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Product, Kyowa Kirin Collaboration		19.20	16.88	21.23	NA	13.18	12.40	9.39	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Product, Mepsevii		5.63	8.44	8.48	4.80	6.04	4.93	4.86	3.11	3.92	5.40	3.61	3.66	4.08	4.18	3.42	4.36	2.36	3.24	2.67	2.65	2.13	2.01	1.12	0.28	0.20	NA	NA	NA
Royalty, Crysvita		55.70	46.33	4.88	6.06	5.37	5.42	4.84	4.74	4.65	4.69	3.87	3.57	3.33	3.48	2.62	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
		13.01	9.95	9.39	10.26	8.41	9.48	8.23	7.08	7.24	6.70	5.64	5.61	5.00	6.55	4.16	3.56	2.79	2.82	2.91	2.08	1.62	0.93	0.66	0.12	0.20	NA	NA	NA
		0.00	0.00	1.18	0.00	1.16	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
		17.23	19.07	22.80	8.26	14.12	12.54	9.79	5.42	7.49	4.71	6.02	3.20	3.82	3.23	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
		67.81	79.29	67.13	84.83	67.01	67.33	61.92	70.89	66.91	75.57	87.74	82.73	72.65	51.93	30.36	30.12	21.70	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
U S And Canada		NA	NA	NA	NA	67.01	67.33	61.92	NA	66.91	75.57	87.74	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Revenue From Contract With Customer Excluding Assessed Tax		98.05	108.31	100.50	103.35	90.70	89.34	79.94	83.39	81.65	86.97	99.39	91.54	81.47	61.71	36.31	35.59	25.80	24.15	18.17	16.26	11.76	12.79	10.68	2.41	0.20	0.01	0.11	0.02
Daiichi Sankyo Co Ltd, Collaboration And License		0.00	0.00	1.48	1.48	1.48	1.48	3.25	8.23	12.06	21.96	42.75	37.50	32.87	18.86	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Collaboration And License		0.00	19.80	51.38	68.38	52.83	53.09	48.41	58.44	55.05	63.94	79.01	75.02	66.92	50.16	27.21	28.42	21.59	19.25	14.24	12.80	9.02	10.52	9.36	NA	NA	NA	NA	NA
Product		42.35	42.18	44.23	28.91	32.50	30.83	26.68	20.21	21.95	18.35	16.51	12.96	11.21	8.07	6.48	7.17	4.21	4.90	3.93	3.46	2.75	2.27	1.31	0.28	0.20	NA	NA	NA
Royalty		55.70	46.33	4.88	6.06	5.37	5.42	4.84	4.74	4.65	4.69	3.87	3.57	3.33	3.48	2.62	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Product, License Agreement Terms, Kyowa Kirin Collaboration		NA	NA	NA	7.70	13.20	12.40	9.40	5.20	7.40	2.90	5.90	3.00	3.30	2.50	1.60	1.60	1.10	1.00	0.60	0.30	0.30	NA	NA	NA	NA	NA	NA	NA
Collaboration, United States And Canada, Kyowa Kirin Collaboration		0.00	19.80	NA	NA	51.35	51.61	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Collaboration And Royalty, European Union And Switzerland And Turkey, Kyowa Kirin Collaboration		NA	NA	NA	NA	NA	NA	4.84	0.00	0.02	0.23	3.87	-0.00	0.00	1.50	NA	2.22	1.95	1.93	2.02	NA	NA	NA	NA	NA	NA	NA	NA	NA
Collaboration And Royalty, United States And Canada, Kyowa Kirin Collaboration		50.23	61.31	49.91	66.90	51.35	51.61	45.16	50.21	42.97	41.76	36.26	37.52	34.06	29.81	27.21	26.15	19.53	17.25	11.94	NA	NA	NA	NA	NA	NA	NA	NA	NA
Non Cash Royalty, European Union And Switzerland And Turkey, Kyowa Kirin Collaboration		5.47	4.82	NA	NA	5.37	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Non Cash Royalty, United States And Canada, Kyowa Kirin Collaboration		15.07	12.45	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Royalty, European Union And Switzerland And Turkey, Kyowa Kirin Collaboration		NA	4.82	4.88	6.06	5.37	5.42	50.00	4.74	4.65	4.69	3.87	3.57	3.33	3.48	2.62	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Royalty, United States And Canada, Kyowa Kirin Collaboration		35.16	29.06	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Collaboration And License, Crysvita		0.00	19.80	49.91	66.90	51.35	51.61	45.16	50.21	42.97	41.76	36.26	37.52	34.06	29.81	27.21	26.15	19.53	17.25	11.94	NA	NA	NA	NA	NA	NA	NA	NA	NA
Collaboration And Royalty, Kyowa Kirin Collaboration		74.90	83.01	76.02	72.96	56.72	57.03	59.40	54.95	47.64	46.67	40.13	41.09	37.39	34.79	29.83	28.37	21.48	19.18	13.95	NA	NA	NA	NA	NA	NA	NA	NA	NA
Product, Crysvita		19.20	16.88	21.23	7.70	13.18	12.40	9.39	5.27	7.38	2.90	5.87	2.91	3.28	2.55	1.61	1.55	1.14	1.01	0.59	0.35	0.27	0.03	NA	NA	NA	NA	NA	NA
Product, Dojolvi		16.55	16.49	14.30	16.41	13.27	13.50	12.43	11.82	10.65	10.05	7.03	6.39	3.86	1.33	1.44	1.26	0.71	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Product, Evkeeza		0.96	0.36	0.21	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Product, Kyowa Kirin Collaboration		19.20	16.88	21.23	NA	13.18	12.40	9.39	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Product, Mepsevii		5.63	8.44	8.48	4.80	6.04	4.93	4.86	3.11	3.92	5.40	3.61	3.66	4.08	4.18	3.42	4.36	2.36	3.24	2.67	2.65	2.13	2.01	1.12	0.28	0.20	NA	NA	NA
Royalty, Crysvita		55.70	46.33	4.88	6.06	5.37	5.42	4.84	4.74	4.65	4.69	3.87	3.57	3.33	3.48	2.62	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
		13.01	9.95	9.39	10.26	8.41	9.48	8.23	7.08	7.24	6.70	5.64	5.61	5.00	6.55	4.16	3.56	2.79	2.82	2.91	2.08	1.62	0.93	0.66	0.12	0.20	NA	NA	NA
		0.00	0.00	1.18	0.00	1.16	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
		17.23	19.07	22.80	8.26	14.12	12.54	9.79	5.42	7.49	4.71	6.02	3.20	3.82	3.23	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
		67.81	79.29	67.13	84.83	67.01	67.33	61.92	70.89	66.91	75.57	87.74	82.73	72.65	51.93	30.36	30.12	21.70	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
U S And Canada		NA	NA	NA	NA	67.01	67.33	61.92	NA	66.91	75.57	87.74	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA

Plots across concepts

Line plots across dimensions of each concept