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| 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Common Stock Value | 0.01 | 0.01 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | NA | NA | NA | |
| Weighted Average Number Of Diluted Shares Outstanding | 55.55 | 55.28 | 49.27 | NA | 42.26 | 38.34 | 32.72 | NA | 32.39 | 32.32 | 32.23 | NA | 27.02 | 26.74 | NA | NA | NA | NA | NA | |
| Weighted Average Number Of Shares Outstanding Basic | 55.55 | 55.28 | 49.27 | NA | 42.26 | 38.34 | 32.72 | NA | 32.39 | 32.32 | 32.23 | NA | 27.02 | 26.74 | NA | NA | NA | NA | NA | |
| Earnings Per Share Basic | -0.79 | -0.63 | -0.66 | -0.77 | -0.24 | -0.77 | -0.88 | -0.84 | -0.79 | -0.87 | -0.82 | -0.85 | -0.82 | -0.28 | NA | NA | NA | NA | NA | |
| Earnings Per Share Diluted | -0.79 | -0.63 | -0.66 | -0.77 | -0.24 | -0.77 | -0.88 | -0.84 | -0.79 | -0.87 | -0.82 | -0.85 | -0.82 | -0.28 | NA | NA | NA | NA | NA |
| 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue From Contract With Customer Excluding Assessed Tax | 0.00 | 0.01 | 0.03 | -0.02 | 20.20 | 0.24 | 0.30 | 1.25 | 0.50 | 0.16 | 1.22 | 0.09 | 1.37 | 14.58 | 2.00 | -0.98 | 7.42 | 3.51 | 3.41 | |
| Revenues | 0.00 | 0.01 | 0.03 | -0.02 | 20.20 | 0.24 | 0.30 | 1.25 | 0.50 | 0.16 | 1.22 | 0.09 | 1.37 | 14.58 | 2.00 | -0.98 | 7.42 | 3.63 | 3.54 | |
| Operating Expenses | 51.13 | 42.46 | 38.16 | 36.63 | 34.18 | 32.38 | 30.40 | 29.97 | 27.00 | 28.59 | 27.61 | 24.86 | 24.03 | 22.18 | 18.31 | 19.45 | 15.24 | 18.78 | 16.81 | |
| Research And Development Expense Excluding Acquired In Process Cost | 38.48 | 31.86 | 27.87 | 26.03 | 25.07 | 23.58 | 22.41 | 21.50 | 18.94 | 20.42 | 19.38 | 17.53 | 15.84 | 15.22 | 12.77 | NA | NA | NA | NA | |
| General And Administrative Expense | 12.65 | 10.60 | 10.29 | 10.61 | 9.11 | 8.79 | 7.99 | 8.47 | 8.05 | 8.17 | 8.23 | 7.33 | 8.19 | 6.95 | 5.54 | 6.84 | 3.68 | 3.06 | 3.65 | |
| Operating Income Loss | -51.13 | -42.46 | -38.14 | -36.65 | -13.97 | -32.14 | -30.11 | -28.72 | -26.50 | -28.43 | -26.39 | -24.76 | -22.66 | -7.60 | -16.31 | -20.42 | -7.82 | -15.15 | -13.28 | |
| Allocated Share Based Compensation Expense | 6.49 | 6.07 | 5.97 | 5.91 | 4.56 | 4.97 | 4.22 | 4.35 | 4.52 | 4.32 | 3.93 | 3.73 | 3.92 | 3.82 | 2.33 | 1.72 | 1.15 | 1.04 | 1.08 | |
| Profit Loss | -43.84 | -34.95 | -32.40 | -32.28 | -10.26 | -29.62 | -28.68 | -27.38 | -25.69 | -28.09 | -26.34 | -25.08 | -22.24 | -7.59 | -16.41 | -20.55 | -7.83 | -15.15 | -13.16 | |
| Net Income Loss | -43.84 | -34.95 | -32.40 | -32.28 | -10.26 | -29.62 | -28.68 | -27.38 | -25.69 | -28.09 | -26.34 | -25.08 | -22.24 | -7.59 | -16.41 | -20.55 | -7.83 | -15.15 | -13.16 | |
| Comprehensive Income Net Of Tax | -42.47 | -35.14 | -32.53 | -32.80 | -10.07 | -29.00 | -27.76 | -26.72 | -25.71 | -28.49 | -27.34 | -25.31 | -22.43 | -7.59 | -16.41 | -20.55 | -7.83 | NA | NA | |
| Net Income Loss Available To Common Stockholders Basic | -43.84 | -34.95 | -32.40 | -32.28 | -10.26 | -29.62 | -28.68 | -27.38 | -25.69 | -28.09 | -26.34 | -25.08 | -22.24 | -7.59 | -16.41 | -20.55 | -7.83 | -15.15 | -13.16 |
| 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Assets | 604.03 | 620.12 | 629.88 | 339.89 | 361.61 | 352.50 | 244.02 | 261.85 | 280.16 | 302.94 | 324.93 | 353.49 | 240.62 | 254.93 | 270.11 | 288.33 | NA | NA | NA | |
| Liabilities | 51.08 | 31.78 | 29.32 | 32.06 | 31.68 | 27.36 | 25.41 | 30.51 | 28.72 | 30.42 | 28.87 | 34.38 | 16.48 | 14.29 | 27.68 | 31.94 | NA | NA | NA | |
| Liabilities And Stockholders Equity | 604.03 | 620.12 | 629.88 | 339.89 | 361.61 | 352.50 | 244.02 | 261.85 | 280.16 | 302.94 | 324.93 | 353.49 | 240.62 | 254.93 | 270.11 | 288.33 | NA | NA | NA | |
| Stockholders Equity | 552.95 | 588.34 | 600.56 | 307.83 | 329.93 | 325.14 | 218.61 | 231.34 | 251.44 | 272.52 | 296.06 | 319.11 | 224.13 | 240.65 | 242.43 | 256.39 | -105.29 | -99.16 | -85.04 |
| 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Assets Current | 510.76 | 552.63 | 535.59 | 296.59 | 328.24 | 317.78 | 207.04 | 220.51 | 232.48 | 246.52 | 243.05 | 256.28 | 165.73 | 248.75 | 264.50 | 282.66 | NA | NA | NA | |
| Cash And Cash Equivalents At Carrying Value | 187.54 | 189.06 | 275.59 | 249.11 | 275.68 | 236.31 | 78.57 | 52.35 | 108.30 | 113.48 | 75.97 | 153.00 | 90.99 | 243.74 | 259.87 | 276.73 | NA | NA | NA | |
| Marketable Securities Current | 314.35 | 352.88 | 250.32 | 39.12 | 43.99 | 74.03 | 121.89 | 161.20 | 119.42 | 127.60 | 160.18 | 94.78 | NA | NA | NA | NA | NA | NA | NA | |
| Prepaid Expense And Other Assets Current | 8.87 | 10.69 | 9.68 | 8.36 | 8.58 | 7.43 | 6.59 | 6.96 | 4.76 | 5.43 | 6.89 | 8.46 | 3.27 | 3.79 | 3.67 | 4.44 | NA | NA | NA |
| 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Property Plant And Equipment Gross | 35.36 | 33.06 | 32.57 | 32.06 | 31.57 | 31.13 | 30.37 | 29.99 | 28.77 | 27.29 | 24.19 | 19.72 | 13.76 | 10.17 | 9.23 | 8.92 | NA | NA | NA | |
| Accumulated Depreciation Depletion And Amortization Property Plant And Equipment | 15.49 | 14.30 | 13.11 | 11.93 | 10.83 | 9.84 | 8.76 | 7.73 | 6.71 | 6.20 | 5.73 | 5.33 | 4.97 | 4.59 | 4.22 | 3.84 | NA | NA | NA | |
| Property Plant And Equipment Net | 19.87 | 18.76 | 19.46 | 20.13 | 20.74 | 21.30 | 21.61 | 22.26 | 22.05 | 21.10 | 18.46 | 14.39 | 8.79 | 5.58 | 5.01 | 5.07 | NA | NA | NA | |
| Other Assets Noncurrent | 2.86 | 2.32 | 0.77 | 0.68 | 0.68 | 1.08 | 1.26 | 1.08 | 1.05 | 0.96 | 0.88 | 0.60 | 0.60 | 0.60 | 0.60 | 0.60 | NA | NA | NA |
| 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Liabilities Current | 29.46 | 19.40 | 16.40 | 18.95 | 18.16 | 13.75 | 11.28 | 15.73 | 13.56 | 14.33 | 12.09 | 16.34 | 11.37 | 9.87 | 13.92 | 16.74 | NA | NA | NA | |
| Accounts Payable Current | 2.92 | 3.43 | 4.22 | 3.52 | 4.71 | 3.49 | 2.41 | 3.32 | 1.48 | 3.32 | 2.68 | 4.76 | 3.71 | 1.96 | 1.28 | 1.79 | NA | NA | NA | |
| Other Accrued Liabilities Current | 0.12 | 0.10 | 0.14 | 0.10 | 0.16 | 0.05 | 0.04 | 0.38 | 0.19 | 0.75 | 0.21 | 1.77 | 0.42 | 0.36 | 0.30 | 0.49 | NA | NA | NA | |
| Accrued Liabilities Current | 21.41 | 12.78 | 9.01 | 12.01 | 10.19 | 6.58 | 5.41 | 8.87 | 7.24 | 6.16 | 5.26 | 7.74 | NA | NA | NA | 8.37 | NA | NA | NA | |
| Contract With Customer Liability Current | 0.04 | NA | NA | 0.27 | 0.13 | 0.58 | 0.78 | 0.88 | 2.21 | 2.26 | 2.11 | 2.60 | 1.73 | 3.02 | 7.09 | 6.59 | NA | NA | NA |
| 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Other Liabilities Noncurrent | 0.20 | 0.21 | 0.23 | 0.25 | 0.02 | 0.02 | 0.03 | 0.02 | 0.02 | 0.01 | 0.01 | 0.12 | 1.89 | 1.87 | 1.86 | 1.85 | NA | NA | NA | |
| Operating Lease Liability Noncurrent | 19.74 | 10.46 | 11.00 | 11.52 | 12.03 | 12.53 | 13.01 | 13.47 | 13.92 | 14.40 | 14.78 | 15.22 | NA | NA | NA | NA | NA | NA | NA |
| 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stockholders Equity | 552.95 | 588.34 | 600.56 | 307.83 | 329.93 | 325.14 | 218.61 | 231.34 | 251.44 | 272.52 | 296.06 | 319.11 | 224.13 | 240.65 | 242.43 | 256.39 | -105.29 | -99.16 | -85.04 | |
| Common Stock Value | 0.01 | 0.01 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | NA | NA | NA | |
| Additional Paid In Capital Common Stock | 1078.39 | 1071.31 | 1048.39 | 723.14 | 712.44 | 697.58 | 562.04 | 547.02 | 540.40 | 535.76 | 530.81 | 526.52 | 406.24 | 400.32 | 394.51 | 392.06 | NA | NA | NA | |
| Retained Earnings Accumulated Deficit | -526.52 | -482.68 | -447.73 | -415.33 | -383.04 | -372.79 | -343.17 | -314.49 | -287.11 | -261.42 | -233.33 | -207.00 | -181.91 | -159.67 | -152.09 | -135.68 | NA | NA | NA | |
| Accumulated Other Comprehensive Income Loss Net Of Tax | 1.08 | -0.29 | -0.11 | 0.02 | 0.53 | 0.34 | -0.27 | -1.20 | -1.85 | -1.83 | -1.42 | -0.42 | -0.20 | NA | NA | NA | NA | NA | NA | |
| Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value | 6.49 | 6.07 | 5.97 | NA | 4.56 | 4.97 | 4.22 | NA | 4.52 | 4.32 | 3.93 | NA | 3.92 | 3.82 | 2.33 | NA | 1.15 | 1.04 | 1.08 |
| 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Cash Provided By Used In Operating Activities | -29.39 | -30.24 | -29.09 | -24.65 | -1.17 | -22.07 | -27.91 | -22.21 | -21.02 | -19.90 | -23.55 | -21.84 | -15.72 | -16.20 | -15.37 | -17.50 | -13.37 | -6.17 | -13.87 | |
| Net Cash Provided By Used In Investing Activities | 27.30 | -73.54 | -263.26 | -6.68 | 29.98 | 49.29 | 43.13 | -35.78 | 15.37 | 57.47 | -54.11 | -32.29 | -139.01 | -0.74 | -0.64 | -0.51 | 0.35 | -0.12 | -0.72 | |
| Net Cash Provided By Used In Financing Activities | 0.57 | 17.25 | 318.83 | 4.76 | 10.56 | 130.52 | 10.99 | 2.05 | 0.46 | -0.05 | 0.63 | 116.14 | 1.98 | 0.82 | -0.85 | 205.98 | 0.90 | 72.49 | -0.39 |
| 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Cash Provided By Used In Operating Activities | -29.39 | -30.24 | -29.09 | -24.65 | -1.17 | -22.07 | -27.91 | -22.21 | -21.02 | -19.90 | -23.55 | -21.84 | -15.72 | -16.20 | -15.37 | -17.50 | -13.37 | -6.17 | -13.87 | |
| Net Income Loss | -43.84 | -34.95 | -32.40 | -32.28 | -10.26 | -29.62 | -28.68 | -27.38 | -25.69 | -28.09 | -26.34 | -25.08 | -22.24 | -7.59 | -16.41 | -20.55 | -7.83 | -15.15 | -13.16 | |
| Profit Loss | -43.84 | -34.95 | -32.40 | -32.28 | -10.26 | -29.62 | -28.68 | -27.38 | -25.69 | -28.09 | -26.34 | -25.08 | -22.24 | -7.59 | -16.41 | -20.55 | -7.83 | -15.15 | -13.16 | |
| Increase Decrease In Accounts Payable | -0.51 | -0.79 | 0.70 | -1.09 | 1.37 | 0.95 | -0.33 | 1.51 | -1.70 | 0.23 | -1.68 | 1.66 | 0.80 | 0.43 | -0.60 | 0.57 | -2.77 | 2.58 | -0.33 | |
| Share Based Compensation | 6.49 | 6.07 | 5.97 | 5.91 | 4.56 | 4.97 | 4.22 | 4.35 | 4.52 | 4.32 | 3.93 | 3.73 | 3.92 | 3.82 | 2.33 | 1.72 | 1.15 | 1.04 | 1.08 |
| 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Cash Provided By Used In Investing Activities | 27.30 | -73.54 | -263.26 | -6.68 | 29.98 | 49.29 | 43.13 | -35.78 | 15.37 | 57.47 | -54.11 | -32.29 | -139.01 | -0.74 | -0.64 | -0.51 | 0.35 | -0.12 | -0.72 | |
| Payments To Acquire Property Plant And Equipment | 1.78 | 0.35 | 0.71 | 0.55 | 0.41 | 0.81 | 1.01 | 1.09 | 1.96 | 2.07 | 6.41 | 5.10 | 2.63 | 0.74 | 0.64 | 0.51 | -0.35 | 0.12 | 0.72 |
| 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Cash Provided By Used In Financing Activities | 0.57 | 17.25 | 318.83 | 4.76 | 10.56 | 130.52 | 10.99 | 2.05 | 0.46 | -0.05 | 0.63 | 116.14 | 1.98 | 0.82 | -0.85 | 205.98 | 0.90 | 72.49 | -0.39 |
| 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenues | 0.00 | 0.01 | 0.03 | -0.02 | 20.20 | 0.24 | 0.30 | 1.25 | 0.50 | 0.16 | 1.22 | 0.09 | 1.37 | 14.58 | 2.00 | -0.98 | 7.42 | 3.63 | 3.54 | |
| Cystic Fibrosis Foundation, Collaboration And License Revenue | 0.00 | 0.01 | 0.03 | -0.02 | 0.15 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.03 | 0.09 | 0.01 | 0.02 | 0.00 | 0.06 | -0.05 | -0.06 | 0.02 | |
| Collaboration And License Revenue | 0.00 | 0.01 | 0.03 | -0.02 | 20.20 | 0.24 | 0.30 | 1.25 | 0.50 | 0.16 | 1.22 | 0.09 | 1.37 | 14.58 | 2.00 | NA | NA | 3.63 | 3.54 | |
| US | 0.00 | 0.01 | 0.03 | -0.02 | 20.16 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.03 | 0.09 | 0.01 | 0.02 | 0.00 | 0.06 | -0.05 | -0.06 | 0.02 | |
| Revenue From Contract With Customer Excluding Assessed Tax | 0.00 | 0.01 | 0.03 | -0.02 | 20.20 | 0.24 | 0.30 | 1.25 | 0.50 | 0.16 | 1.22 | 0.09 | 1.37 | 14.58 | 2.00 | -0.98 | 7.42 | 3.51 | 3.41 |
