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2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31

Common Stock Value 0.02 0.02 0.02 0.02 0.06 0.06 0.06 0.06 0.06 0.06 0.06 0.04 0.04 0.04 0.04 0.04 0.04 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.02

Weighted Average Number Of Diluted Shares Outstanding 27.91 27.84 NA 9.42 63.82 6.31 NA 6.29 62.86 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA

Weighted Average Number Of Shares Outstanding Basic 27.91 27.84 NA 9.42 63.82 6.31 NA 6.29 62.86 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA

Weighted Average Number Of Share Outstanding Basic And Diluted NA NA NA NA NA 63.06 NA 62.93 62.86 61.38 48.77 45.78 45.70 43.92 42.89 42.44 41.67 33.77 33.69 33.65 32.89 30.34 26.32 26.26 25.58 23.39

Earnings Per Share Basic -1.30 -0.85 4.44 -3.21 -0.54 -3.99 -3.78 -4.14 -0.36 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA

Earnings Per Share Diluted -1.30 -0.85 4.44 -3.21 -0.54 -3.99 -3.78 -4.14 -0.36 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA

Earnings Per Share Basic And Diluted NA NA NA NA NA -0.40 -0.37 -0.41 -0.36 -0.23 -0.62 -0.43 -0.38 -0.39 -0.46 -0.47 -0.47 -0.49 -0.54 -0.47 -0.43 -0.48 -0.58 -0.53 -0.52 -0.49

2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31

Revenue From Contract With Customer Excluding Assessed Tax 2.83 2.95 -0.75 3.89 6.28 5.47 7.80 5.70 5.16 4.83 5.70 3.83 3.19 2.38 0.51 0.60 0.50 0.50 0.89 0.40 0.40 0.40 0.00 0.00 0.00 1.10

Revenues 2.83 2.95 -0.75 3.89 6.28 5.47 7.80 5.70 5.16 4.83 5.70 3.83 3.19 2.38 0.51 0.56 0.46 0.45 0.89 0.41 0.38 0.37 0.00 0.00 0.00 1.10

Operating Expenses 36.83 36.17 35.24 43.34 40.05 32.12 33.23 32.61 31.31 25.77 34.92 22.82 19.93 19.72 20.68 20.95 20.67 17.43 19.50 16.73 14.92 15.19 15.52 14.04 13.51 12.71

Research And Development Expense 29.61 28.76 27.91 25.76 33.10 25.17 26.80 27.26 25.79 20.03 29.03 17.67 14.80 14.57 14.28 15.93 15.47 12.56 15.13 12.86 11.08 11.12 11.78 10.45 10.04 9.63

General And Administrative Expense 7.22 7.41 7.33 8.08 6.95 6.95 6.43 5.35 5.52 5.74 5.89 5.15 5.13 5.15 6.40 5.02 5.20 4.87 4.37 3.88 3.84 4.08 3.74 3.59 3.47 3.09

Operating Income Loss -34.00 -33.21 -36.00 -39.45 -33.77 -26.65 -25.42 -26.91 -26.14 -20.94 -29.22 -19.00 -16.74 -17.34 -20.17 -20.39 -20.21 -16.97 -18.61 -16.32 -14.55 -14.82 -15.52 -14.04 -13.51 -11.61

Interest Expense 1.28 1.22 1.13 1.05 0.98 0.98 0.99 0.98 0.97 0.97 0.54 0.49 0.49 0.27 0.02 0.02 0.02 0.01 NA NA NA NA NA NA NA NA

Interest Paid Net 1.12 1.05 0.99 0.84 0.79 0.78 0.81 0.80 0.80 0.79 0.45 0.41 0.41 0.23 0.02 0.02 0.02 0.01 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00

Allocated Share Based Compensation Expense 2.81 2.65 2.90 2.96 2.69 2.86 2.88 2.10 2.45 2.93 3.03 2.72 2.73 2.46 3.22 2.39 2.36 1.88 1.63 1.54 1.74 1.70 1.27 1.11 1.16 0.88

Profit Loss -36.26 -23.79 -4.77 -30.25 -34.48 -25.15 -23.81 -26.03 -22.49 -14.23 -30.13 -19.49 -17.20 -17.23 -19.73 -19.79 -19.45 -16.46 -18.03 -15.74 -14.05 -14.46 NA NA NA NA

Net Income Loss -36.26 -23.79 -4.77 -30.25 -34.48 -25.15 -23.81 -26.03 -22.49 -14.23 -30.13 -19.49 -17.20 -17.23 -19.73 -19.79 -19.45 -16.46 -18.03 -15.74 -14.05 -14.46 -15.30 -13.82 -13.37 -11.52

Comprehensive Income Net Of Tax -36.47 -23.63 -4.45 -30.17 -34.52 -25.34 -23.89 -26.01 -22.51 -14.23 -30.13 -19.49 -17.20 -17.25 -19.73 -19.78 -19.46 -16.45 -18.02 -15.74 -14.02 -14.46 -15.33 -13.83 -13.36 -11.52

Net Income Loss Available To Common Stockholders Basic -36.26 -23.79 -4.77 -30.25 -34.48 -25.15 -23.81 -26.03 -22.49 -14.23 -30.13 -19.49 -17.20 -17.23 -19.73 -19.79 -19.45 -16.46 -18.03 -15.74 -14.05 -14.46 -15.30 -13.82 -13.37 -11.52

2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31

Assets 180.98 205.32 244.49 284.73 126.23 152.08 182.94 208.04 233.73 260.63 213.25 133.34 147.82 161.40 149.98 143.83 151.83 88.43 106.77 120.63 131.38 128.10 78.49 88.68 99.03 78.02

Liabilities And Stockholders Equity 180.98 205.32 244.49 284.73 126.23 152.08 182.94 208.04 233.73 260.63 213.25 133.34 147.82 161.40 149.98 143.83 151.83 88.43 106.77 120.63 131.38 128.10 78.49 88.68 99.03 78.02

Stockholders Equity 73.24 106.75 127.74 129.17 31.02 62.74 85.22 106.06 129.98 149.88 90.55 45.94 62.41 76.54 79.18 94.57 111.92 64.02 78.59 94.84 108.71 104.50 65.32 78.59 91.08 70.14

2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31

Assets Current 152.63 173.64 211.39 252.31 91.94 116.48 136.59 153.27 186.21 226.68 178.56 98.56 112.45 125.69 114.51 111.02 124.37 77.76 101.73 115.54 126.95 123.37 73.16 83.17 93.19 72.50

Cash And Cash Equivalents At Carrying Value 115.44 104.77 167.47 171.53 59.06 69.58 92.30 115.42 160.91 222.14 173.98 93.13 108.67 116.87 41.44 33.36 101.74 22.13 49.89 43.52 114.39 94.33 32.20 42.15 79.53 48.00

Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents 118.53 107.85 170.55 174.62 62.15 72.66 95.39 118.51 164.00 225.23 177.07 96.22 111.76 119.96 44.82 37.38 105.75 26.14 50.81 44.45 114.68 94.82 32.69 42.63 80.01 48.48

Marketable Securities Current 28.54 61.04 34.84 72.95 27.22 40.69 38.07 30.16 21.11 NA NA NA NA 5.00 49.98 74.77 19.98 53.74 49.79 69.71 9.98 27.41 39.84 39.80 11.99 22.50

Prepaid Expense And Other Assets Current 6.89 6.08 7.39 6.05 3.37 3.03 3.24 4.05 2.00 1.91 2.24 3.12 2.17 2.18 2.65 2.24 2.01 1.26 1.42 1.68 2.58 1.44 0.92 1.03 1.67 1.46

2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31

Property Plant And Equipment Gross NA NA 23.91 NA NA NA 22.70 NA NA NA 21.43 NA NA NA 19.65 NA NA NA 9.16 NA NA NA 7.64 NA NA NA

Accumulated Depreciation Depletion And Amortization Property Plant And Equipment NA NA 12.55 NA NA NA 9.86 NA NA NA 7.22 NA NA NA 4.44 NA NA NA 5.30 NA NA NA 3.70 NA NA NA

Property Plant And Equipment Net 10.30 10.95 11.35 12.06 11.99 12.55 12.84 13.46 13.78 13.93 14.21 15.02 15.36 15.76 15.21 11.15 5.44 3.90 3.86 3.91 3.27 3.56 3.94 4.13 4.51 4.55

Other Assets Noncurrent 2.23 4.65 5.35 3.67 5.32 3.15 2.94 2.41 2.44 1.74 1.97 1.01 1.04 0.78 0.49 0.93 0.89 1.10 0.88 0.89 0.86 0.88 1.10 1.09 0.85 0.49

2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31

Liabilities Current 28.38 23.55 30.78 38.42 38.93 27.59 31.51 29.88 27.62 27.37 28.62 28.06 23.20 19.81 23.52 22.57 15.33 14.98 19.53 21.30 17.68 21.34 12.41 9.24 7.02 6.87

Long Term Debt Current NA 1.67 NA NA 6.67 1.67 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA

Accounts Payable Current 6.69 2.79 6.41 13.02 6.12 2.84 3.69 4.11 3.67 3.66 3.60 4.94 2.80 4.64 5.85 8.04 1.76 2.63 3.31 2.67 1.26 1.72 2.28 1.85 1.35 2.38

2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31

Long Term Debt NA NA NA 40.51 40.63 40.44 40.00 40.00 40.00 40.00 40.00 20.00 NA NA NA NA NA NA NA NA NA NA NA NA NA NA

Long Term Debt Noncurrent 40.93 39.12 40.65 40.51 33.97 38.77 40.26 40.07 39.89 39.72 39.55 19.72 19.64 NA NA NA NA NA NA NA NA NA NA NA NA NA

Operating Lease Liability Noncurrent 19.73 20.30 20.85 21.39 21.89 22.38 22.86 23.32 23.75 24.17 24.58 24.97 25.34 24.24 24.02 18.43 16.25 0.77 NA NA NA NA NA NA NA NA

2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31

Stockholders Equity 73.24 106.75 127.74 129.17 31.02 62.74 85.22 106.06 129.98 149.88 90.55 45.94 62.41 76.54 79.18 94.57 111.92 64.02 78.59 94.84 108.71 104.50 65.32 78.59 91.08 70.14

Common Stock Value 0.02 0.02 0.02 0.02 0.06 0.06 0.06 0.06 0.06 0.06 0.06 0.04 0.04 0.04 0.04 0.04 0.04 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.02

Additional Paid In Capital Common Stock 691.45 688.49 685.85 682.84 554.48 551.68 548.82 545.77 543.67 541.07 467.52 392.79 389.77 386.70 372.10 367.76 365.33 297.98 296.10 294.33 292.46 274.23 220.61 218.54 217.20 182.90

Retained Earnings Accumulated Deficit -618.28 -582.02 -558.23 -553.46 -523.21 -488.73 -463.58 -439.77 -413.74 -391.25 -377.02 -346.89 -327.40 -310.21 -292.98 -273.25 -253.46 -234.01 -217.54 -199.51 -183.78 -169.73 -155.27 -139.96 -126.14 -112.77

Accumulated Other Comprehensive Income Loss Net Of Tax 0.05 0.26 0.10 -0.23 -0.31 -0.27 -0.08 -0.01 -0.02 NA NA NA NA 0.00 0.02 0.02 0.00 0.01 -0.00 -0.01 -0.01 -0.03 -0.04 -0.01 -0.01 -0.01

Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value 2.81 2.65 2.90 2.96 2.69 2.86 2.88 2.10 2.45 2.93 3.03 2.72 2.73 2.46 3.22 2.39 2.36 1.88 1.63 1.54 1.74 1.70 NA NA NA NA

2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31

Net Cash Provided By Used In Operating Activities -22.39 -36.90 -31.08 -35.79 -26.18 -30.02 -22.97 -28.13 -26.45 -21.99 -29.92 -15.26 -12.43 0.25 -10.60 -11.22 -18.10 -20.33 -13.81 -10.03 -14.08 -2.40 -10.57 -9.53 -11.81 -12.82

Net Cash Provided By Used In Investing Activities 32.92 -25.75 37.72 6.19 15.89 7.38 -0.24 -17.30 -34.84 -0.26 -0.03 -0.52 4.01 43.20 16.95 -57.14 32.68 -4.23 20.04 -60.53 17.48 12.36 -0.07 -27.82 10.19 2.10

Net Cash Provided By Used In Financing Activities 0.14 -0.05 -10.70 142.06 -0.22 -0.09 0.10 -0.07 0.07 70.41 110.80 0.24 0.22 31.69 1.09 -0.01 65.03 -0.12 0.14 0.33 16.45 52.17 0.69 -0.03 33.15 0.13

2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31

Net Cash Provided By Used In Operating Activities -22.39 -36.90 -31.08 -35.79 -26.18 -30.02 -22.97 -28.13 -26.45 -21.99 -29.92 -15.26 -12.43 0.25 -10.60 -11.22 -18.10 -20.33 -13.81 -10.03 -14.08 -2.40 -10.57 -9.53 -11.81 -12.82

Net Income Loss -36.26 -23.79 -4.77 -30.25 -34.48 -25.15 -23.81 -26.03 -22.49 -14.23 -30.13 -19.49 -17.20 -17.23 -19.73 -19.79 -19.45 -16.46 -18.03 -15.74 -14.05 -14.46 -15.30 -13.82 -13.37 -11.52

Profit Loss -36.26 -23.79 -4.77 -30.25 -34.48 -25.15 -23.81 -26.03 -22.49 -14.23 -30.13 -19.49 -17.20 -17.23 -19.73 -19.79 -19.45 -16.46 -18.03 -15.74 -14.05 -14.46 NA NA NA NA

Depreciation Depletion And Amortization 0.65 0.64 0.70 0.66 0.66 0.68 0.71 0.70 0.68 0.67 0.70 0.70 0.69 0.68 0.83 0.58 0.59 0.52 0.43 0.41 0.38 0.39 0.39 0.39 0.38 0.36

Increase Decrease In Accounts Payable 3.90 -3.62 2.44 -2.00 3.30 -0.97 -0.29 0.34 -0.07 0.06 -1.16 2.26 -1.09 -1.06 1.40 1.64 -0.94 -0.61 0.52 1.38 -0.45 -0.56 0.44 0.49 -1.01 0.22

Share Based Compensation 2.81 2.65 2.90 2.96 2.69 2.86 2.88 2.10 2.45 2.93 3.03 2.72 2.73 2.46 3.22 2.39 2.35 1.88 1.63 1.54 1.74 1.70 1.27 1.11 1.16 0.88

2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31

Net Cash Provided By Used In Investing Activities 32.92 -25.75 37.72 6.19 15.89 7.38 -0.24 -17.30 -34.84 -0.26 -0.03 -0.52 4.01 43.20 16.95 -57.14 32.68 -4.23 20.04 -60.53 17.48 12.36 -0.07 -27.82 10.19 2.10

Payments To Acquire Property Plant And Equipment -0.00 0.23 0.67 0.33 0.11 0.13 0.24 0.31 0.43 0.26 0.03 0.52 0.99 1.80 8.16 2.57 1.32 0.59 0.20 1.02 0.02 0.15 0.07 0.05 0.31 0.40

2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31

Net Cash Provided By Used In Financing Activities 0.14 -0.05 -10.70 142.06 -0.22 -0.09 0.10 -0.07 0.07 70.41 110.80 0.24 0.22 31.69 1.09 -0.01 65.03 -0.12 0.14 0.33 16.45 52.17 0.69 -0.03 33.15 0.13

2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31

Revenues 2.83 2.95 -0.75 3.89 6.28 5.47 7.80 5.70 5.16 4.83 5.70 3.83 3.19 2.38 0.51 0.56 0.46 0.45 0.89 0.41 0.38 0.37 0.00 0.00 0.00 1.10

Revenue From Contract With Customer Excluding Assessed Tax 2.83 2.95 -0.75 3.89 6.28 5.47 7.80 5.70 5.16 4.83 5.70 3.83 3.19 2.38 0.51 0.60 0.50 0.50 0.89 0.40 0.40 0.40 0.00 0.00 0.00 1.10

Incyte NA NA 0.10 0.20 0.60 0.40 1.30 0.10 1.90 0.80 2.20 0.30 0.70 0.20 0.50 0.60 0.50 0.50 NA NA NA NA NA NA NA NA

Global Blood Therapeutics, Collaborative Arrangement 2.80 3.00 -0.80 3.70 5.70 5.10 6.50 5.60 3.30 4.00 3.50 3.50 2.50 2.20 NA NA NA NA NA NA NA NA NA NA NA NA

Plots across concepts

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Operating Lease Right Of Use Asset

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Property Plant And Equipment Net

Current Assets

Prepaid Expense And Other Assets Current

NonCurrent Assets

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NetCashProvidedByUsedInInvestingActivities

Payments To Acquire Property Plant And Equipment

Shares

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