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| 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Common Stock Value | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.02 | 0.02 | 0.02 | NA | 0.00 | NA | NA | |
| Weighted Average Number Of Diluted Shares Outstanding | 251.32 | 250.20 | 249.59 | NA | 248.32 | 246.31 | 244.18 | NA | 239.38 | 42.71 | 17.27 | NA | NA | NA | |
| Weighted Average Number Of Shares Outstanding Basic | 251.32 | 250.20 | 249.59 | NA | 248.32 | 246.31 | 244.18 | NA | 239.38 | 42.71 | 17.27 | NA | NA | NA | |
| Earnings Per Share Basic | -0.20 | -0.26 | -0.27 | -0.03 | -0.28 | -0.15 | -0.28 | -0.18 | -0.20 | -1.47 | -3.19 | NA | NA | NA | |
| Earnings Per Share Diluted | -0.20 | -0.26 | -0.27 | -0.03 | -0.28 | -0.15 | -0.28 | -0.18 | -0.20 | -1.47 | -3.19 | NA | NA | NA |
| 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenues | 0.03 | 0.03 | 0.07 | 48.39 | 0.00 | 35.74 | 0.55 | 2.82 | 2.75 | 2.63 | 2.44 | 2.31 | 1.07 | 3.12 | |
| Operating Expenses | 59.06 | 65.93 | 62.62 | 63.17 | 66.44 | 73.00 | 69.13 | 50.36 | 51.92 | 65.33 | 57.81 | 41.84 | 37.91 | 105.68 | |
| Research And Development Expense | 43.85 | 47.47 | 44.63 | 38.03 | 41.61 | 43.72 | 35.83 | 19.29 | 31.43 | 46.45 | 41.53 | 35.09 | 24.50 | 97.15 | |
| General And Administrative Expense | 15.51 | 19.03 | 19.28 | 26.35 | 26.08 | 30.45 | 34.42 | 31.87 | 21.24 | 19.11 | 16.83 | 14.87 | 13.57 | 9.56 | |
| Operating Income Loss | -59.04 | -65.91 | -62.56 | -14.78 | -66.44 | -37.26 | -68.58 | -47.54 | -49.16 | -62.71 | -55.37 | -39.52 | -36.84 | -102.57 | |
| Interest Income Expense Nonoperating Net | 6.61 | 5.26 | 4.50 | 3.45 | 2.25 | 0.95 | 0.40 | 0.32 | 0.27 | 0.22 | 0.35 | NA | NA | NA | |
| Allocated Share Based Compensation Expense | 10.52 | 14.22 | 13.88 | 18.36 | 19.12 | 22.41 | 22.03 | 21.18 | 13.04 | 15.25 | 12.73 | 12.97 | 9.75 | 7.27 | |
| Other Comprehensive Income Loss Net Of Tax | 1.20 | 1.50 | 3.72 | 2.40 | -1.65 | -1.75 | -4.98 | -1.56 | -0.14 | -0.09 | -0.09 | -0.34 | -0.60 | 0.10 | |
| Net Income Loss | -50.85 | -63.89 | -66.96 | -8.40 | -70.25 | -36.32 | -68.14 | -83.71 | -48.88 | -62.59 | -55.04 | -38.86 | -35.72 | -100.66 | |
| Comprehensive Income Net Of Tax | -49.66 | -62.39 | -63.24 | -6.00 | -71.90 | -38.07 | -73.12 | -85.26 | -49.01 | -62.69 | -55.14 | -39.19 | -36.32 | -100.55 |
| 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Assets | 794.99 | 835.35 | 880.45 | 937.56 | 977.27 | 1021.67 | 1072.10 | 1127.41 | 1198.33 | 1229.87 | NA | 908.28 | NA | NA | |
| Liabilities | 97.42 | 98.50 | 96.62 | 104.31 | 157.24 | 153.63 | 190.85 | 197.62 | 211.86 | 207.91 | NA | 189.84 | NA | NA | |
| Liabilities And Stockholders Equity | 794.99 | 835.35 | 880.45 | 937.56 | 977.27 | 1021.67 | 1072.10 | 1127.41 | 1198.33 | 1229.87 | NA | 908.28 | NA | NA | |
| Stockholders Equity | 697.57 | 736.86 | 783.83 | 833.25 | 820.03 | 868.04 | 881.25 | 929.79 | 986.47 | 1021.96 | -334.05 | -292.53 | -266.64 | -240.11 |
| 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Assets Current | 586.85 | 606.41 | 624.40 | 651.29 | 659.75 | 666.78 | 625.71 | 626.29 | 631.15 | 834.84 | NA | 617.55 | NA | NA | |
| Cash And Cash Equivalents At Carrying Value | 286.21 | 224.37 | 109.43 | 123.55 | 116.31 | 205.74 | 222.60 | 293.83 | 393.50 | 564.44 | 244.37 | 140.41 | 134.41 | 245.95 | |
| Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents | 286.50 | 224.65 | 109.71 | 123.83 | 116.59 | 206.02 | 222.88 | 294.29 | 393.97 | 564.91 | 244.84 | 140.87 | 134.88 | 246.42 | |
| Marketable Securities Current | 289.22 | 371.38 | 503.34 | 516.60 | 531.82 | 449.82 | 391.32 | 320.97 | 225.42 | 260.08 | NA | 472.21 | NA | NA | |
| Prepaid Expense And Other Assets Current | 11.42 | 10.66 | 11.63 | 11.14 | 11.61 | 11.21 | 11.79 | 11.49 | 12.23 | 10.32 | NA | 4.93 | NA | NA | |
| Equity Securities Fv Ni | NA | NA | NA | NA | NA | 1.08 | 1.09 | 1.07 | NA | NA | NA | 1.32 | NA | NA |
| 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Property Plant And Equipment Gross | NA | NA | NA | 155.41 | NA | NA | NA | 134.61 | NA | NA | NA | 82.15 | NA | NA | |
| Accumulated Depreciation Depletion And Amortization Property Plant And Equipment | NA | NA | NA | 32.38 | NA | NA | NA | 14.51 | NA | NA | NA | 5.10 | NA | NA | |
| Property Plant And Equipment Net | 108.10 | 113.68 | 118.60 | 123.02 | 125.73 | 127.56 | 125.71 | 120.10 | 115.86 | 109.64 | NA | 77.05 | NA | NA | |
| Other Assets Noncurrent | 4.42 | 4.52 | 4.60 | 4.68 | 2.91 | 3.71 | 3.57 | 3.48 | 2.67 | 2.79 | NA | 2.77 | NA | NA | |
| Equity Securities Fv Ni | NA | NA | NA | NA | NA | 1.08 | 1.09 | 1.07 | NA | NA | NA | 1.32 | NA | NA |
| 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Liabilities Current | 35.06 | 34.39 | 30.80 | 37.03 | 51.22 | 50.29 | 41.05 | 46.74 | 59.28 | 63.66 | NA | 49.28 | NA | NA | |
| Accounts Payable Current | 4.37 | 5.80 | 5.73 | 3.92 | 4.79 | 4.25 | 6.51 | 3.21 | 3.53 | 4.86 | NA | 9.40 | NA | NA | |
| Other Accrued Liabilities Current | NA | NA | NA | 2.35 | NA | NA | NA | 1.47 | NA | NA | NA | 0.66 | NA | NA | |
| Contract With Customer Liability Current | NA | NA | NA | NA | 11.19 | 15.43 | 6.22 | 4.99 | 5.58 | 8.23 | NA | 6.09 | NA | NA |
| 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Other Liabilities Noncurrent | 3.78 | 3.89 | 4.00 | 4.11 | 4.23 | 4.34 | 4.45 | 4.57 | 5.01 | 0.90 | NA | 0.53 | NA | NA | |
| Operating Lease Liability Noncurrent | 58.58 | 60.22 | 61.83 | 63.17 | 64.64 | 66.07 | 67.47 | 66.65 | 65.68 | 61.47 | NA | 50.96 | NA | NA |
| 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stockholders Equity | 697.57 | 736.86 | 783.83 | 833.25 | 820.03 | 868.04 | 881.25 | 929.79 | 986.47 | 1021.96 | -334.05 | -292.53 | -266.64 | -240.11 | |
| Common Stock Value | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.02 | 0.02 | 0.02 | NA | 0.00 | NA | NA | |
| Additional Paid In Capital | 1647.91 | 1637.54 | 1622.12 | 1608.31 | 1589.08 | 1565.20 | 1540.33 | 1515.75 | NA | NA | NA | 41.36 | NA | NA | |
| Retained Earnings Accumulated Deficit | -949.18 | -898.33 | -834.44 | -767.48 | -759.08 | -688.83 | -652.51 | -584.36 | -500.66 | -451.78 | NA | -334.14 | NA | NA | |
| Accumulated Other Comprehensive Income Loss Net Of Tax | -1.18 | -2.38 | -3.88 | -7.60 | -10.00 | -8.35 | -6.60 | -1.62 | -0.07 | 0.07 | NA | 0.26 | NA | NA | |
| Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value | 10.52 | 14.22 | 13.88 | 18.36 | 19.12 | 22.41 | 22.03 | 21.18 | 13.04 | 15.25 | 12.73 | 12.97 | 9.78 | 7.27 |
| 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Cash Provided By Used In Operating Activities | -37.69 | -39.16 | -46.21 | -40.27 | -37.10 | -44.33 | -47.85 | -33.17 | -25.53 | -33.95 | -33.60 | -26.73 | -21.63 | NA | |
| Net Cash Provided By Used In Investing Activities | 99.67 | 152.91 | 32.15 | 46.65 | -57.09 | 25.02 | -26.12 | -73.90 | -144.87 | -39.47 | 136.68 | 32.39 | -89.94 | NA | |
| Net Cash Provided By Used In Financing Activities | -0.14 | 1.20 | -0.07 | 0.86 | 4.76 | 2.46 | 2.56 | 7.40 | -0.53 | 393.49 | 0.88 | 0.34 | 0.04 | NA |
| 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Cash Provided By Used In Operating Activities | -37.69 | -39.16 | -46.21 | -40.27 | -37.10 | -44.33 | -47.85 | -33.17 | -25.53 | -33.95 | -33.60 | -26.73 | -21.63 | NA | |
| Net Income Loss | -50.85 | -63.89 | -66.96 | -8.40 | -70.25 | -36.32 | -68.14 | -83.71 | -48.88 | -62.59 | -55.04 | -38.86 | -35.72 | -100.66 | |
| Depreciation Depletion And Amortization | 5.10 | 5.06 | 5.03 | 5.04 | 4.62 | 4.17 | 4.19 | 4.57 | 4.09 | 3.01 | 1.96 | 1.45 | 1.10 | NA | |
| Increase Decrease In Accounts Payable | -1.41 | 0.38 | 2.07 | -0.53 | 0.02 | -1.77 | 2.94 | 0.10 | -0.99 | 0.35 | 0.63 | 0.34 | -0.29 | NA | |
| Share Based Compensation | 10.52 | 14.22 | 13.88 | 18.36 | 19.12 | 22.41 | 22.03 | 21.18 | 13.04 | 15.25 | 12.73 | 12.97 | 9.75 | NA |
| 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Cash Provided By Used In Investing Activities | 99.67 | 152.91 | 32.15 | 46.65 | -57.09 | 25.02 | -26.12 | -73.90 | -144.87 | -39.47 | 136.68 | 32.39 | -89.94 | NA | |
| Payments To Acquire Property Plant And Equipment | 0.20 | 0.93 | 1.53 | 4.58 | 2.79 | 7.17 | 9.73 | 10.27 | 11.60 | 24.45 | 19.19 | 24.88 | 12.64 | NA |
| 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Cash Provided By Used In Financing Activities | -0.14 | 1.20 | -0.07 | 0.86 | 4.76 | 2.46 | 2.56 | 7.40 | -0.53 | 393.49 | 0.88 | 0.34 | 0.04 | NA |
| 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenues | 0.03 | 0.03 | 0.07 | 48.39 | 0.00 | 35.74 | 0.55 | 2.82 | 2.75 | 2.63 | 2.44 | 2.31 | 1.07 | 3.12 | |
| Glaxo Smith Kline Intellectual Property No5 Limited And Glaxo Group Limited, Adjustment To Revenue Related To Change In Estimate, Collaborative Arrangement Transaction With Party To Collaborative Arrangement | NA | NA | NA | 48.30 | 0.00 | 35.30 | NA | NA | NA | NA | NA | NA | NA | NA | |
| Glaxo Smith Kline Intellectual Property No5 Limited And Glaxo Group Limited, Adjustment To Revenue Related To Change In Estimate, Collaborative Arrangement Transaction With Party To Collaborative Arrangement | NA | NA | NA | 48.30 | 0.00 | 35.30 | NA | NA | NA | NA | NA | NA | NA | NA | |
| GSK, Related Party | NA | NA | NA | NA | 0.00 | 35.70 | NA | NA | NA | NA | NA | NA | NA | NA | |
| Glaxo Smith Kline Intellectual Property No5 Limited And Glaxo Group Limited, Collaborative Arrangement Transaction With Party To Collaborative Arrangement | NA | NA | NA | 48.40 | 0.00 | 35.70 | 0.60 | 2.80 | 2.60 | 2.60 | 2.40 | NA | NA | NA |
