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Tables

		2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30
Common Stock Value		0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.00
Earnings Per Share Basic		-0.26	-0.33	-0.31	-0.30	-0.30	-0.35	-0.34	-0.34	-0.36	-0.36	-0.33	0.10	NA	NA	NA	-0.71	NA	NA	NA	NA	NA	NA
Earnings Per Share Diluted		-0.26	-0.33	-0.31	-0.30	-0.30	-0.35	-0.34	-0.34	-0.36	-0.36	-0.33	0.10	NA	NA	NA	-0.71	NA	NA	NA	NA	NA	NA

		2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30
Revenue From Contract With Customer Excluding Assessed Tax		10.38	1.56	1.96	2.44	4.26	3.02	5.47	7.19	3.06	2.61	2.84	39.69	1.35	0.94	0.49	1.26	0.88	0.98	1.15	1.35	1.09	0.10
Revenues		10.38	1.56	1.96	2.44	4.26	3.02	5.47	7.19	3.06	2.61	2.84	39.69	1.35	0.94	0.49	1.26	0.88	0.98	1.15	1.35	1.09	0.10
Operating Expenses		40.85	40.17	37.68	37.26	36.18	32.90	35.14	36.15	32.85	30.77	28.01	31.80	28.50	27.08	26.55	27.93	29.20	29.47	23.36	20.28	19.12	18.71
Research And Development Expense		32.94	32.76	30.97	30.51	29.42	26.44	27.35	28.20	26.17	24.40	22.07	24.86	22.84	22.05	21.29	22.47	23.58	24.89	18.53	15.90	15.25	15.62
General And Administrative Expense		7.92	7.41	6.72	6.75	6.76	6.46	7.79	7.96	6.68	6.37	5.94	6.94	5.66	5.03	5.25	5.46	5.62	4.58	4.83	4.38	3.87	3.09
Operating Income Loss		-30.47	-38.60	-35.73	-34.82	-31.92	-29.88	-29.67	-28.96	-29.78	-28.16	-25.17	7.90	-27.15	-26.14	-26.06	-26.67	-28.31	-28.48	-22.21	-18.93	-18.03	-18.61
Interest Expense		1.22	0.99	0.98	0.84	0.68	0.55	NA	0.02	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Interest Paid Net		0.67	0.67	0.64	0.44	0.44	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Interest Income Expense Nonoperating Net		0.88	1.17	1.48	1.68	1.31	0.46	0.15	0.05	0.01	0.04	0.05	0.03	-0.02	0.07	0.19	0.47	0.61	0.94	1.04	0.92	0.69	0.03
Allocated Share Based Compensation Expense		2.82	2.96	2.94	2.89	3.01	3.06	3.35	3.13	2.80	2.82	2.73	2.20	1.70	1.84	1.96	1.62	1.44	1.53	1.32	1.01	1.32	0.54
Net Income Loss		-30.82	-38.43	-35.26	-33.98	-31.29	-29.97	-29.52	-28.92	-29.77	-28.12	-25.12	7.92	-27.17	-26.07	-25.87	-26.21	-27.70	-27.55	-21.17	-18.01	-17.34	-18.59
Comprehensive Income Net Of Tax		-30.76	-38.36	-35.33	-33.95	-31.09	-29.84	-29.53	-29.23	-29.85	-28.12	-25.10	7.92	-27.17	-26.12	-25.80	-26.25	-27.71	-27.59	-21.16	-17.86	-17.42	-18.56

		2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30
Assets		177.77	187.22	222.62	209.95	240.75	205.24	213.95	243.47	278.11	271.28	224.22	246.94	221.57	122.51	145.67	163.02	184.39	208.65	228.18	175.49	189.56	113.20
Liabilities		125.92	113.23	113.06	69.07	69.97	68.39	50.58	54.28	62.02	63.33	45.40	47.59	54.83	50.52	49.44	47.63	50.05	52.26	45.80	43.27	40.44	40.51
Liabilities And Stockholders Equity		177.77	187.22	222.62	209.95	240.75	205.24	213.95	243.47	278.11	271.28	224.22	246.94	221.57	122.51	145.67	163.02	184.39	208.65	228.18	175.49	189.56	113.20
Stockholders Equity		51.85	73.98	109.57	140.88	170.78	136.85	163.38	189.19	216.09	207.96	178.82	199.35	166.74	71.98	96.23	115.39	134.34	156.40	182.38	132.22	149.12	72.69

		2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30
Assets Current		87.44	90.82	122.38	154.76	182.88	153.43	161.74	192.50	220.59	218.40	176.75	202.51	175.39	73.75	94.50	112.35	131.27	154.78	184.70	135.00	157.64	84.15
Cash And Cash Equivalents At Carrying Value		62.99	29.54	41.41	47.13	55.50	64.91	65.69	69.16	93.29	131.42	64.08	108.50	170.06	57.65	62.63	54.86	57.41	116.94	107.73	34.57	52.18	65.94
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents		70.58	36.07	49.14	54.49	64.77	76.93	80.30	83.84	110.58	148.10	65.07	109.50	171.05	59.22	63.62	55.85	58.40	117.93	108.72	35.56	53.17	66.93
Marketable Securities Current		16.29	54.41	73.12	98.68	116.39	74.90	78.94	103.00	108.35	68.25	107.10	89.50	1.00	12.90	29.28	54.02	70.37	32.52	73.51	97.59	100.93	11.49
Other Assets Current		0.78	0.82	0.72	0.73	0.57	0.80	0.79	0.99	0.87	0.81	0.34	0.51	0.27	0.40	0.29	0.37	0.29	0.81	0.39	0.50	0.45	0.90
Prepaid Expense And Other Assets Current		5.86	5.63	5.41	6.88	7.01	6.89	7.79	10.95	7.67	7.73	5.57	4.51	4.33	3.20	2.58	3.47	3.50	5.32	3.46	2.84	4.53	6.73
Available For Sale Securities Debt Securities		62.27	70.29	105.04	132.55	158.61	116.81	128.26	157.09	194.28	NA	NA	NA	NA	NA	NA	NA	NA	34.53	74.02	127.40	149.12	48.72

		2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30
Property Plant And Equipment Gross		49.68	52.74	51.37	49.59	48.77	46.35	42.69	42.30	41.91	41.51	40.87	40.12	38.96	38.57	38.17	37.78	37.22	33.57	27.00	22.59	36.24	32.69
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment		32.41	33.82	32.10	30.58	28.78	27.02	25.34	23.84	22.28	21.69	20.11	18.52	16.93	15.26	13.59	11.94	10.31	9.20	8.03	6.94	6.75	5.67
Property Plant And Equipment Net		17.28	18.95	20.44	20.36	21.34	21.67	22.71	22.28	21.62	21.34	21.79	21.69	22.11	23.31	24.58	25.85	26.91	24.38	18.97	15.65	29.49	27.01
Available For Sale Debt Securities Amortized Cost Basis		62.26	70.34	105.17	132.61	158.69	117.09	128.68	157.48	194.35	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	127.33	149.21	48.72

		2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30
Liabilities Current		27.34	23.38	22.11	24.67	34.80	32.31	32.39	34.09	39.96	36.31	21.43	21.78	26.99	22.01	19.18	18.44	19.50	22.89	18.07	14.11	15.11	13.72
Accounts Payable Current		3.82	4.26	4.92	5.97	8.69	2.88	2.38	5.64	4.23	3.39	4.79	6.37	9.58	3.28	4.30	5.01	4.62	6.74	5.25	3.62	4.83	3.87
Accrued Liabilities Current		1.21	1.66	1.45	3.12	4.12	2.67	2.04	1.35	0.41	3.02	0.74	0.57	0.68	0.66	0.14	0.41	1.04	2.15	1.80	0.80	0.99	2.24
Contract With Customer Liability Current		2.35	1.30	2.82	2.80	5.13	8.69	11.08	12.32	17.20	13.79	2.94	3.39	3.48	5.53	5.78	4.51	4.96	5.40	5.50	5.42	5.34	NA

		2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30
Long Term Debt		40.14	29.87	29.72	29.58	19.35	19.28	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Long Term Debt Noncurrent		40.14	29.87	29.72	29.58	19.35	19.28	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Other Liabilities Noncurrent		0.71	0.55	0.40	0.25	0.15	0.05	NA	NA	NA	0.40	0.40	0.40	0.40	0.63	NA	NA	0.00	NA	NA	0.00	0.01	0.03
Operating Lease Liability Noncurrent		57.73	59.43	60.82	14.57	15.67	16.75	17.80	18.69	18.94	19.84	16.18	17.62	19.23	20.79	22.26	20.10	20.98	19.43	16.92	17.10	0.00	NA

		2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30
Stockholders Equity		51.85	73.98	109.57	140.88	170.78	136.85	163.38	189.19	216.09	207.96	178.82	199.35	166.74	71.98	96.23	115.39	134.34	156.40	182.38	132.22	149.12	72.69
Common Stock Value		0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.02	0.00
Additional Paid In Capital		711.39	702.75	699.98	695.96	691.91	626.89	623.58	619.86	617.52	579.54	522.29	517.72	493.02	371.10	369.22	362.59	355.29	349.63	348.02	276.70	275.59	3.88
Retained Earnings Accumulated Deficit		-659.56	-628.74	-590.31	-555.05	-521.07	-489.78	-459.81	-430.30	-401.38	-371.62	-343.50	-318.38	-326.30	-299.13	-273.06	-247.19	-220.99	-193.28	-165.74	-144.56	-126.40	-109.06
Accumulated Other Comprehensive Income Loss Net Of Tax		0.00	-0.05	-0.12	-0.05	-0.08	-0.28	-0.41	-0.39	-0.07	0.01	0.01	-0.00	NA	0.01	0.05	-0.02	0.02	0.03	0.08	0.07	-0.09	-0.01
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value		2.82	2.96	2.94	2.89	3.01	3.06	3.35	3.13	2.80	2.82	2.73	2.20	1.70	1.84	1.96	1.62	1.44	1.53	1.32	1.01	1.28	0.54

		2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30
Net Cash Provided By Used In Operating Activities		-19.51	-31.09	-30.96	-40.09	-30.37	-25.78	-26.34	-33.45	-23.78	-14.87	-22.68	10.65	-25.22	-20.18	-20.73	-22.98	-22.45	-25.02	-18.41	-19.13	-13.00	1.90
Net Cash Provided By Used In Investing Activities		38.30	18.28	24.59	21.17	-46.15	3.08	22.48	7.63	-46.63	41.16	-23.49	-89.60	11.62	15.73	23.82	14.77	-41.35	33.98	21.78	1.43	-91.46	14.99
Net Cash Provided By Used In Financing Activities		15.72	-0.26	1.02	8.65	64.36	19.34	0.31	-0.92	32.88	56.74	1.75	17.39	125.43	0.04	4.68	5.66	4.27	0.25	69.79	0.09	90.70	11.50

		2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30
Net Cash Provided By Used In Operating Activities		-19.51	-31.09	-30.96	-40.09	-30.37	-25.78	-26.34	-33.45	-23.78	-14.87	-22.68	10.65	-25.22	-20.18	-20.73	-22.98	-22.45	-25.02	-18.41	-19.13	-13.00	1.90
Net Income Loss		-30.82	-38.43	-35.26	-33.98	-31.29	-29.97	-29.52	-28.92	-29.77	-28.12	-25.12	7.92	-27.17	-26.07	-25.87	-26.21	-27.70	-27.55	-21.17	-18.01	-17.34	-18.59
Increase Decrease In Accounts Payable		-0.58	-0.09	-1.62	0.33	2.82	0.49	-3.30	1.86	0.52	-1.36	-1.22	1.64	1.03	-0.80	-0.27	0.86	-1.55	2.47	-0.63	-0.23	3.07	0.36
Share Based Compensation		2.82	2.96	2.94	2.89	3.01	3.06	3.35	3.13	2.80	2.82	2.73	2.20	1.70	1.84	1.96	1.62	1.44	1.53	1.32	1.01	1.32	0.50
Amortization Of Financing Costs		0.47	0.30	0.29	0.34	0.27	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA

		2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30
Net Cash Provided By Used In Investing Activities		38.30	18.28	24.59	21.17	-46.15	3.08	22.48	7.63	-46.63	41.16	-23.49	-89.60	11.62	15.73	23.82	14.77	-41.35	33.98	21.78	1.43	-91.46	14.99
Payments To Acquire Property Plant And Equipment		0.19	1.09	1.72	1.57	1.48	1.12	1.45	1.81	1.33	1.47	1.67	0.99	0.27	0.62	1.02	1.61	5.60	5.74	2.25	2.58	2.29	0.52

		2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30
Net Cash Provided By Used In Financing Activities		15.72	-0.26	1.02	8.65	64.36	19.34	0.31	-0.92	32.88	56.74	1.75	17.39	125.43	0.04	4.68	5.66	4.27	0.25	69.79	0.09	90.70	11.50

		2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30
Revenues		10.38	1.56	1.96	2.44	4.26	3.02	5.47	7.19	3.06	2.61	2.84	39.69	1.35	0.94	0.49	1.26	0.88	0.98	1.15	1.35	1.09	0.10
Gates Foundation, Grant Agreement		0.40	0.40	0.50	0.40	0.40	0.30	0.30	0.20	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Grant		10.35	1.20	1.55	1.90	2.94	2.58	2.71	2.45	1.28	0.21	NA	NA	0.43	0.14	NA	NA	NA	NA	NA	NA	NA	NA
License		0.03	0.36	0.40	0.54	1.33	0.44	2.76	4.75	1.78	2.40	2.84	39.69	0.92	0.80	NA	NA	0.88	0.98	NA	NA	NA	NA
Revenue From Contract With Customer Excluding Assessed Tax		10.38	1.56	1.96	2.44	4.26	3.02	5.47	7.19	3.06	2.61	2.84	39.69	1.35	0.94	0.49	1.26	0.88	0.98	1.15	1.35	1.09	0.10
Gates Foundation, Grant Agreement		0.40	0.40	0.50	0.40	0.40	0.30	0.30	0.20	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Grant		10.35	1.20	1.55	1.90	2.94	2.58	2.71	2.45	1.28	0.21	NA	NA	0.43	0.14	NA	NA	NA	NA	NA	NA	NA	NA
License		0.03	0.36	0.40	0.54	1.33	0.44	2.76	4.75	1.78	2.40	2.84	39.69	0.92	0.80	NA	NA	0.88	0.98	NA	NA	NA	NA

Plots across concepts

Line plots across dimensions of each concept