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| 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Common Stock Value | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| Earnings Per Share Basic | -0.27 | -0.57 | -0.61 | -0.50 | -0.60 | -0.59 | -0.51 | 1.61 | -0.59 | -0.54 | -0.54 | -0.02 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | |
| Earnings Per Share Diluted | -0.27 | -0.57 | -0.61 | -0.50 | -0.60 | -0.59 | -0.51 | 1.59 | -0.59 | -0.54 | -0.54 | -0.02 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue From Contract With Customer Excluding Assessed Tax | 0.00 | 0.00 | 0.35 | 0.80 | 0.80 | 0.80 | 0.80 | 0.80 | 0.80 | 1.68 | 2.19 | 29.30 | 0.98 | 0.57 | 0.57 | 0.59 | 0.56 | 0.44 | 0.39 | 0.27 | 2.62 | 0.95 | 0.93 | 1.13 | |
| Revenues | 0.00 | 0.00 | 0.35 | 0.80 | 0.80 | 0.80 | 0.80 | 0.80 | 0.80 | 1.68 | 2.19 | 29.30 | 0.98 | 0.57 | 0.57 | 0.59 | 0.56 | 0.44 | 0.39 | 0.27 | 0.98 | 0.95 | 0.93 | 0.82 | |
| Operating Expenses | 12.10 | 31.00 | 31.17 | 28.31 | 35.30 | 33.66 | 29.11 | 38.42 | 34.43 | 32.34 | 32.74 | 30.42 | 30.78 | 28.84 | 36.26 | 37.08 | 26.12 | 31.73 | 28.36 | 25.39 | 21.37 | 17.24 | 14.82 | 11.83 | |
| Research And Development Expense | 1.51 | 17.52 | 22.98 | 19.99 | 27.15 | 25.85 | 21.07 | 24.27 | 23.65 | 23.99 | 23.70 | 21.75 | 23.20 | 20.42 | 27.47 | 29.31 | 20.34 | 25.69 | 22.83 | 20.54 | 16.28 | 13.39 | 10.29 | 8.00 | |
| General And Administrative Expense | 7.90 | 6.84 | 8.19 | 8.32 | 8.15 | 7.81 | 8.03 | 14.15 | 10.78 | 8.35 | 9.04 | 8.66 | 7.59 | 8.42 | 8.79 | 7.77 | 5.78 | 6.04 | 5.54 | 4.86 | 5.09 | 3.84 | 4.53 | 3.83 | |
| Operating Income Loss | -12.10 | -31.00 | -30.82 | -27.51 | -34.49 | -32.86 | -28.31 | -37.62 | -33.62 | -30.66 | -30.55 | -1.11 | -29.80 | -28.27 | -35.70 | -36.49 | -25.56 | -31.29 | -27.97 | -25.12 | -20.39 | -16.28 | -13.89 | -11.00 | |
| Allocated Share Based Compensation Expense | 0.85 | 1.71 | 2.40 | 2.37 | 3.09 | 2.77 | 3.14 | 4.05 | 4.66 | 4.23 | 4.47 | 3.88 | 3.57 | 3.35 | 3.45 | 2.88 | 2.44 | 1.99 | 1.97 | 1.24 | 0.96 | 0.72 | 0.57 | 0.38 | |
| Profit Loss | -16.12 | -32.95 | -35.04 | -28.84 | -34.30 | -33.73 | -29.09 | 92.11 | -33.58 | -30.61 | -30.50 | -1.07 | -29.79 | -28.23 | -35.34 | -35.33 | -24.17 | -29.63 | -26.27 | -23.85 | -19.00 | -14.80 | -13.20 | -10.22 | |
| Net Income Loss | -16.12 | -32.95 | -35.04 | -28.84 | -34.30 | -33.73 | -29.09 | 92.11 | -33.58 | -30.61 | -30.50 | -1.07 | -29.79 | -28.23 | -35.34 | -35.33 | -24.17 | -29.63 | -26.27 | -23.85 | -19.00 | -14.80 | -12.89 | -10.52 | |
| Comprehensive Income Net Of Tax | -16.09 | -32.90 | -34.95 | -28.62 | -34.24 | -34.14 | -29.13 | 92.11 | -33.59 | -30.61 | -30.48 | -1.10 | -29.79 | -28.24 | -35.31 | -35.53 | -24.24 | -29.56 | -26.09 | -23.77 | -19.06 | -14.77 | -12.86 | -10.54 |
| 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Assets | 84.56 | 140.06 | 169.34 | 197.88 | 228.47 | 262.65 | 284.61 | 310.96 | 211.72 | 230.82 | 258.92 | 234.70 | 263.74 | 228.36 | 258.24 | 288.79 | 310.57 | 316.76 | 341.16 | 233.03 | 259.09 | 268.40 | 270.31 | 129.08 | |
| Liabilities | 11.57 | 51.85 | 49.96 | 45.98 | 50.49 | 53.59 | 44.32 | 44.70 | 42.07 | 32.24 | 34.34 | 33.87 | 67.74 | 58.14 | 63.53 | 62.25 | 52.06 | 58.94 | 56.41 | 58.76 | 64.38 | 55.64 | 43.52 | 40.84 | |
| Liabilities And Stockholders Equity | 84.56 | 140.06 | 169.34 | 197.88 | 228.47 | 262.65 | 284.61 | 310.96 | 211.72 | 230.82 | 258.92 | 234.70 | 263.74 | 228.36 | 258.24 | 288.79 | 310.57 | 316.76 | 341.16 | 233.03 | 259.09 | 268.40 | 270.31 | 129.08 | |
| Stockholders Equity | 72.99 | 88.21 | 119.38 | 151.90 | 177.98 | 209.06 | 240.29 | 266.25 | 169.65 | 198.57 | 224.58 | 200.83 | 196.00 | 170.22 | 194.70 | 226.54 | 258.51 | 257.82 | 284.74 | 174.26 | 194.72 | 212.76 | 226.80 | -49.52 |
| 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Assets Current | 83.91 | 106.64 | 131.34 | 153.58 | 181.01 | 213.20 | 238.44 | 262.45 | 191.91 | 191.82 | 217.94 | 191.65 | 219.56 | 181.25 | 209.81 | 238.33 | 266.58 | 274.08 | 298.77 | 190.50 | 221.69 | 245.87 | 261.58 | 120.40 | |
| Cash And Cash Equivalents At Carrying Value | 39.27 | 29.11 | 76.80 | 39.45 | 33.99 | 43.16 | 176.19 | 248.13 | 108.38 | 95.83 | 116.31 | 104.42 | 217.43 | 178.00 | 167.64 | 143.37 | 53.77 | 77.56 | 115.57 | 40.84 | 38.22 | 36.04 | 94.96 | 46.21 | |
| Prepaid Expense And Other Assets Current | 1.00 | 3.02 | 4.26 | 3.56 | 5.99 | 12.13 | 12.92 | 6.32 | 7.13 | 4.27 | 4.64 | 3.00 | 2.13 | 3.25 | 3.16 | 3.40 | 4.19 | 4.41 | 2.97 | 2.54 | 6.95 | 8.32 | 6.07 | 3.67 | |
| Available For Sale Securities Debt Securities | 43.39 | 74.19 | 50.27 | 110.57 | 141.04 | 157.91 | 49.34 | 8.00 | 47.49 | 91.72 | 96.98 | 84.23 | NA | NA | 206.39 | 234.68 | 262.14 | 270.20 | 295.31 | 187.49 | 214.27 | 237.96 | 254.94 | NA |
| 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Available For Sale Debt Securities Amortized Cost Basis | 43.39 | 74.22 | 50.36 | 110.75 | 141.44 | 158.37 | 49.38 | 8.00 | 47.50 | 91.73 | 96.98 | 84.26 | NA | NA | 206.38 | 234.70 | 261.95 | 269.95 | 295.13 | 187.48 | 214.34 | 237.98 | 254.99 | NA |
| 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Liabilities Current | 11.57 | 25.29 | 22.94 | 18.51 | 22.58 | 25.25 | 20.73 | 20.80 | 17.23 | 18.70 | 19.53 | 17.81 | 22.66 | 17.18 | 19.56 | 17.45 | 12.37 | 18.68 | 15.49 | 17.65 | 25.43 | 18.57 | 10.88 | 9.44 | |
| Accounts Payable Current | 3.23 | 7.80 | 3.39 | 3.63 | 1.14 | 4.83 | 3.76 | 9.88 | 2.37 | 3.52 | 5.70 | 4.88 | 4.72 | 3.32 | 7.10 | 7.40 | 2.61 | 8.80 | 8.33 | 11.79 | 15.73 | 11.12 | 5.02 | 3.78 | |
| Other Accrued Liabilities Current | 0.33 | 0.20 | 0.76 | 0.16 | 2.26 | 0.51 | 0.31 | 0.19 | 0.04 | 0.23 | 0.18 | 0.37 | 0.20 | 0.31 | 0.25 | 0.22 | 0.26 | 0.44 | 0.29 | 0.18 | 0.30 | NA | NA | NA |
| 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stockholders Equity | 72.99 | 88.21 | 119.38 | 151.90 | 177.98 | 209.06 | 240.29 | 266.25 | 169.65 | 198.57 | 224.58 | 200.83 | 196.00 | 170.22 | 194.70 | 226.54 | 258.51 | 257.82 | 284.74 | 174.26 | 194.72 | 212.76 | 226.80 | -49.52 | |
| Common Stock Value | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| Additional Paid In Capital Common Stock | 615.09 | NA | NA | NA | 607.51 | 604.35 | 601.44 | 598.27 | 593.78 | 589.12 | 584.51 | 530.29 | 524.36 | 468.80 | 465.03 | 461.56 | 457.99 | 433.07 | 430.43 | 293.87 | 292.19 | 291.17 | 290.44 | 1.26 | |
| Retained Earnings Accumulated Deficit | -542.10 | -525.98 | -493.02 | -457.98 | -429.14 | -394.84 | -361.12 | -332.03 | -424.13 | -390.55 | -359.94 | -329.44 | -328.37 | -298.58 | -270.35 | -235.00 | -199.67 | -175.51 | -145.88 | -119.61 | -97.40 | -78.39 | -63.60 | -50.70 | |
| Accumulated Other Comprehensive Income Loss Net Of Tax | -0.01 | -0.04 | -0.09 | -0.18 | -0.40 | -0.46 | -0.04 | NA | -0.01 | -0.01 | 0.00 | -0.02 | NA | NA | 0.01 | -0.02 | 0.18 | 0.25 | 0.19 | 0.01 | -0.08 | -0.02 | -0.05 | -0.09 |
| 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Cash Provided By Used In Operating Activities | -21.57 | -24.94 | -23.66 | -26.05 | -27.20 | -24.93 | -30.85 | -30.68 | -30.43 | -25.39 | -24.11 | -29.82 | -11.61 | -28.89 | -27.99 | -25.85 | -26.33 | -25.48 | -21.67 | -17.87 | -8.08 | -13.69 | -9.75 | -11.04 | |
| Net Cash Provided By Used In Investing Activities | 31.72 | -22.76 | 61.00 | 31.37 | 17.99 | -108.22 | -41.37 | 168.31 | 43.66 | 4.52 | -13.74 | -85.23 | -0.95 | 38.84 | 52.01 | 115.00 | -20.03 | -13.14 | -38.30 | 19.67 | 10.22 | -45.25 | -93.39 | 6.64 | |
| Net Cash Provided By Used In Financing Activities | 0.01 | 0.02 | 0.00 | 0.15 | 0.03 | 0.12 | 0.00 | 0.44 | 0.00 | 0.38 | 49.75 | 2.04 | 51.99 | 0.41 | 0.24 | 0.45 | 22.57 | 0.61 | 134.70 | 0.33 | 0.04 | 0.02 | 151.89 | -0.96 |
| 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Cash Provided By Used In Operating Activities | -21.57 | -24.94 | -23.66 | -26.05 | -27.20 | -24.93 | -30.85 | -30.68 | -30.43 | -25.39 | -24.11 | -29.82 | -11.61 | -28.89 | -27.99 | -25.85 | -26.33 | -25.48 | -21.67 | -17.87 | -8.08 | -13.69 | -9.75 | -11.04 | |
| Net Income Loss | -16.12 | -32.95 | -35.04 | -28.84 | -34.30 | -33.73 | -29.09 | 92.11 | -33.58 | -30.61 | -30.50 | -1.07 | -29.79 | -28.23 | -35.34 | -35.33 | -24.17 | -29.63 | -26.27 | -23.85 | -19.00 | -14.80 | -12.89 | -10.52 | |
| Profit Loss | -16.12 | -32.95 | -35.04 | -28.84 | -34.30 | -33.73 | -29.09 | 92.11 | -33.58 | -30.61 | -30.50 | -1.07 | -29.79 | -28.23 | -35.34 | -35.33 | -24.17 | -29.63 | -26.27 | -23.85 | -19.00 | -14.80 | -13.20 | -10.22 | |
| Increase Decrease In Accounts Payable | -4.57 | 4.41 | -0.24 | 2.49 | -3.69 | 1.07 | -6.06 | 7.70 | -1.36 | -2.11 | 1.09 | -0.10 | 1.97 | -4.43 | 0.08 | 4.84 | -5.96 | 0.94 | 0.66 | -0.09 | 4.95 | -3.14 | 2.06 | 0.51 | |
| Share Based Compensation | 0.85 | 1.71 | 2.40 | 2.37 | 3.09 | 2.77 | 3.14 | 4.05 | 4.66 | 4.23 | 4.47 | 3.88 | 3.57 | 3.35 | 3.45 | 2.88 | 2.44 | 1.99 | 1.97 | 1.24 | 0.96 | 0.72 | 0.57 | 0.38 |
| 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Cash Provided By Used In Investing Activities | 31.72 | -22.76 | 61.00 | 31.37 | 17.99 | -108.22 | -41.37 | 168.31 | 43.66 | 4.52 | -13.74 | -85.23 | -0.95 | 38.84 | 52.01 | 115.00 | -20.03 | -13.14 | -38.30 | 19.67 | 10.22 | -45.25 | -93.39 | 6.64 | |
| Payments To Acquire Property Plant And Equipment | 0.00 | 0.00 | 0.00 | 0.23 | 0.01 | 0.01 | 0.12 | 1.15 | 0.34 | 0.48 | 0.76 | 0.82 | 0.95 | 0.16 | 0.59 | 2.03 | 3.73 | 1.72 | 5.92 | 10.47 | 15.93 | 4.82 | 3.15 | 1.04 |
| 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Cash Provided By Used In Financing Activities | 0.01 | 0.02 | 0.00 | 0.15 | 0.03 | 0.12 | 0.00 | 0.44 | 0.00 | 0.38 | 49.75 | 2.04 | 51.99 | 0.41 | 0.24 | 0.45 | 22.57 | 0.61 | 134.70 | 0.33 | 0.04 | 0.02 | 151.89 | -0.96 |
| 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenues | 0.00 | 0.00 | 0.35 | 0.80 | 0.80 | 0.80 | 0.80 | 0.80 | 0.80 | 1.68 | 2.19 | 29.30 | 0.98 | 0.57 | 0.57 | 0.59 | 0.56 | 0.44 | 0.39 | 0.27 | 0.98 | 0.95 | 0.93 | 0.82 | |
| Revenue From Contract With Customer Excluding Assessed Tax | 0.00 | 0.00 | 0.35 | 0.80 | 0.80 | 0.80 | 0.80 | 0.80 | 0.80 | 1.68 | 2.19 | 29.30 | 0.98 | 0.57 | 0.57 | 0.59 | 0.56 | 0.44 | 0.39 | 0.27 | 2.62 | 0.95 | 0.93 | 1.13 | |
| Pfizer Inc, Collaborative Arrangement | 0.00 | 0.00 | 0.40 | 0.80 | 0.80 | 0.80 | 0.80 | 0.80 | 0.80 | 0.80 | 0.80 | 0.80 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
